• 1
    Matson DD 1964 Craniopharyngioma. Clin Neurosurg 10:116129.
  • 2
    Thomsett MJ, Conte FA, Kaplan SL, Grumbach MM 1980 Endocrine and neurologic outcome in childhood craniopharyngioma: Review of effect of treatment in 42 patients. J Pediatr 97:728735.
  • 3
    Carmel PW, Antunes JL, Chang CH 1982 Craniopharyngiomas in children. Neurosurgery 11:382389.
  • 4
    Lyen KR, Grant DB 1982 Endocrine function, morbidity, and mortality after surgery for craniopharyngioma. Arch Dis Child 57:837841.
  • 5
    Bucher H, Zapf J, Torresani T, Prader A, Froesch ER, Illig R 1983 Insulin-like growth factors I and II, prolactin and insulin in 19 growth hormone-deficient children with excessive, normal, or decreased longitudinal growth after operation for craniopharyngioma. N Engl J Med 309:11421146.
  • 6
    Stahnke N, Grubel G, Lagenstein I, Willig RP 1984 Long-term follow-up of children with craniopharyngioma. Eur J Pediatr 142:179185.
  • 7
    Sorva R 1988 Children with craniopharyngioma: Early growth failure and rapid postoperative weight gain. Acta Pediatr Scand 77:587592.
  • 8
    Vignolo M, Naselli A, Di Battista E, Mostert M, Aicardi G 1988 Growth and development in simple obesity. Eur J Pediatr 147:242244.
  • 9
    Vanderschueren-Lodeweyckx M 1993 The effect of simple obesity on growth and growth hormone. Horm Res 40:2330.
  • 10
    Veldhuis JD, Iranmanesh A, Ho KKY, Waters MJ, Johnson ML, Lizarralde G 1991 Dual effects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J Clin Endocrinol Metab 72:5159.
  • 11
    Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF 1996 Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292295.
  • 12
    Hassink SG, Sheslow DV, de Lancey E, Opentanova I, Considine RV, Caro JF 1996 Serum leptin in children with obesity: Relationship to gender and development. Pediatrics 98:201203.
  • 13
    Zhang Y, Proenca R, Maffei M, Barone M, Lori L, Friedman JM 1994 Positional cloning of the mouse obese gene and its human homologue. Nature 372:425432.
  • 14
    Cinti S, Frederich RC, Zingarreti MC, Dematteis R, Flier JS, Lowell BB 1997 Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue. Endocrinology 138:797804.
  • 15
    Tartaglia LA, Demsbski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI 1995 Identification and expression cloning of a Leptin Receptor, OB-R. Cell 83:12631271.
  • 16
    Houseknecht KL, Baile CA, Matteri RL, Spurlock ME 1998 The biology of Leptin: A review. Journal of Animal Science 76:14051420.
  • 17
    Maor G, Segev Y, Phillip M 1999 Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle—a model of endochondral ossification. Endocrinology 140:19011910.
  • 18
    Maor G, Hochberg Z, Silbermann M 1993 Insulin-like growth factor I accelerates proliferation and differentiation of cartilage progenitor cells in cultures of neonatal mandibular condyles. Acta Endocrinol (Copenh) 128:5664.
  • 19
    Flier JS 1997 Leptin expression and action: New experimental paradigms. Proc Natl Acad Sci USA 94:42424245.
  • 20
    Bennett BD, Solar GP, Yuan JQ, Mathias J, Thomas GR, Matthews W 1996 A role for leptin and its cognate receptor in hematopoiesis. Curr Biol 6:11701180.
  • 21
    Gainsford T, Willson TA, Metcalf D, Handman E, Mcfarlane C, Ng A, Nicola NA, Alexander WS, Hilton DJ 1996 Leptin can induce proliferation, differentiation, and functional activation of hematopoietic cells. Proc Natl Acad Sci USA 93:1456414568.
  • 22
    Bai Y, Zhang S, Kim KS, Lee JK, Kim KH 1996 Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones. J Biol Chem 271:1393913942.
  • 23
    Cohen B, Novick D, Rubinstein M 1996 Modulation of insulin activities by leptin. Science 274:11851188.
  • 24
    Shimabukuro M, Koyama K, Chen G, Wang MY, Trieu F, Lee Y, Newgard CB, Unger RH 1997 Direct antidiabetic effect of leptin through triglyceride depletion of tissues. Proc Natl Acad Sci USA 94:46374641.
  • 25
    Thomas T, Gori F, Khosla S, Jensen MD, Burguera B, Riggs BL 1999 Leptin acts on human stromal marrow cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 140:16301638.
  • 26
    Kitawaki J, Kusuki I, Koshiba H, Tsukamoto K, Honjo H 1999 Leptin directly stimulates aromatase activity in human luteinized granulosa cells. Mol Hum Reprod 5:708713.
  • 27
    Ranganathan S, Ciaraldi TP, Henry RR, Mudaliar S, Kern PH 1998 Lack of effect of leptin on glucose transport, lipoprotein lipase, and insulin action in adipose and muscle cells. Endocrinology 139:25092513.
  • 28
    Tena-sempere M, Pinilla L, Gonzalez LC, Dieguez C, Casanueva FF, Aguilar E 1999 Leptin inhibits testosterone secretion from adult rat testis in vitro. Journal of Endocrinology 161:211218.
  • 29
    Grasso P, White DW, Tartaglia LA, Leinung MC, Lee DW 1999 Inhibitory effects of Leptin-Related synthetic peptide 116–130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Diabetes 48:22042209.
  • 30
    Meistas MT, Foster GV, Margolis S, Kowarski AA 1982 Integrated concentrations of growth hormone, insulin, c-peptide and prolactin in human obesity. Metabolism 31:12241228.
  • 31
    Csizmadi I, Brazeau P, Serri O 1989 Effect of dietary restriction and repeated growth hormone-releasing factor injections on growth hormone response to growth hormone-releasing factor in obese subjects. Metabolism 38:10161021.
  • 32
    Davies RR, Turner SJ, Cook D, Alberti KG, Johnston DG 1985 The response of obese subjects to continuous infusion of human pancreatic growth hormone-releasing factor 1–44. Clin Endocrinol (Oxf) 23::521525.
  • 33
    Kopelman PG, Noonan K, Goulton R, Forrest AJ 1985 Impaired growth hormone response to growth hormone releasing factor and insulin-hypoglycemia in obesity. Clin Endocrinol (Oxf) 23:8794.
  • 34
    Singh SK, Agrawal JK, Rai M, Gupta SS 1991 Growth hormone response to clonidine in obese children. Indian Pediatr 28:737740.
  • 35
    Park MJ, Kim HS, Kang JH, Kim DH, Chung CY 1999 Serum levels of insulin-like growth factor (IGF)-I, free IGF-I, IGF binding protein (IGFBP)-1, IGFBP-3 and insulin in obese children. J Pediatr Endocrinol Metab 12:139144.
  • 36
    Van Vliet G, Bosson D, Rummens E, Robyn C, Wolter R 1986 Evidence against growth hormone-releasing factor deficiency in children with idiopathic obesity. Acta Endocrinol 279:403410.
  • 37
    Attia N, Tamborlane WV, Heptulla R, Maggs D, Grozman A, Sherwin RS, Caprio S 1998 The metabolic syndrome and insulin-like growth factor I regulation in adolescent obesity. J Clin Endocrinol Metab 83:14671471.
  • 38
    Costin G, Kogut MD, Phillips LS, Daughaday WH 1976 Craniopharyngioma: The role of insulin in promoting postoperative growth. J Clin Endocrinol Metab 42:370379.
  • 39
    Holmes LB, Frantz AG, Rabkin MT, Soeldner JS, Crawford JD 1968 Normal growth with subnormal growth hormone levels. N Engl J Med 279:559566.
  • 40
    Kenny FM, Iturzaeta NF, Mintz D, Drash A, Garces LY, Susen A, Askari HA 1968 Iatrogenic hypopituitarism in craniopharyngiomas: Unexplained catch-up growth in three children. J Pediatr 72:766775.
  • 41
    Silverman LA, Grumbach MM, Conte FA 1993 Growth and acromegaloid features in a hypophysectomized (HY) male: The role of prandial hyperinsulinism (HI) [abstract]. Pediatr Res 33(Suppl):565.
  • 42
    Finkelstein JW, Kream J, Ludam A, Hellman L 1972 Sulfation factor (somatomedin): An explanation for continued growth in the absence of immunoassayable growth hormone in patients with hypothalamic tumors. J Clin Endocrinol Metab 35:1317.
  • 43
    Bistritzer T, Lovchik JC, Chalew SA, Kowarski AA 1988 Growth without growth hormone: The “invisible” GH syndrome. Lancet 1:321323.
  • 44
    Geffner ME 1996 The growth without growth hormone syndrome. Endocrinol Metab Clin North Am 25:649663.