• 1
    Fisher LW, Termine JD, Dejter SW Jr, Whitson SW, Yanagishita M, Kimura JH, Hascall VC, Kleinman HK, Hassell JR, Nilsson B 1983 Proteoglycans of developing bone. J Biol Chem 258:65886594.
  • 2
    Fisher LW, Termine JD, Young MF 1989 Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species. J Biol Chem 264:45714576.
  • 3
    Hocking AM, Shinomura T, McQuillan DJ 1998 Leucine-rich repeat glycoproteins of the extracellular matrix. Matrix Biol 17:119.
  • 4
    Iozzo RV 1998 Matrix proteoglycans. From molecular design to cellular function. Ann Rev Biochem 67:609652.
  • 5
    Geerkens C, Vetter U, Just W, Fedarko NS, Fisher LW, Young MF, Termine JD, Robey PG, Wohrle D, Vogel W 1995 The X-chromosomal human biglycan gene BGN is subject to X inactivation but is transcribed like an X-Y homologous gene. Hum Genet 96:4452.
  • 6
    Hausser H, Groning A, Hasilik A, Schonherr E, Kresse H 1994 Selective inactivity of TGF-beta/decorin complexes. FEBS Lett 353:243245.
  • 7
    Ruoslahti E 1989 Proteoglycans in cell regulation. J Biol Chem 264:1336913372.
  • 8
    Iozzo RV 1999 The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. J Biol Chem 274:1884318846.
  • 9
    Vogel KG, Trotter JA 1987 The effect of proteoglycans on the morphology of collagen fibrils formed in vitro. Coll Relat Res 7:105114.
  • 10
    Hedbom E, Heinegärd D 1993 Binding of fibromodulin and decorin to separate sites on fibrillar collagens. J Biol Chem 268:2730727312.
  • 11
    Rada JA, Cornuet PK, Hassell JR 1993 Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan (lumican and decorin) core proteins. Exp Eye Res 56:635648.
  • 12
    Kresse H, Hausser H, Schonherr E, Bittner K 1994 Biosynthesis and interactions of small chondroitin/dermatan sulphate proteoglycans. Eur J Clin Chem Clin Biochem 32:259264.
  • 13
    Schonherr E, Hausser H, Beavan L, Kresse H 1995 Decorin-type I collagen interaction. Presence of separate core protein- binding domains. J Biol Chem 270:88778883.
  • 14
    Schonherr E, Witsch-Prehm P, Harrach B, Robenek H, Rauterberg J, Kresse H 1995 Interaction of biglycan with type I collagen. J Biol Chem 270:27762783.
  • 15
    Kadler KE, Holmes DF, Trotter JA, Chapman JA 1996 Collagen fibril formation. Biochem J 316:111.
  • 16
    Kuc IM, Scott PG 1997 Increased diameters of collagen fibrils precipitated in vitro in the presence of decorin from various connective tissues. Connect Tissue Res 36:287296.
  • 17
    Bianco P, Fisher LW, Young MF, Termine JD, Robey PG 1990 Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues. J Histochem Cytochem 38:15491563.
  • 18
    Danielson KG, Baribault H, Holmes DF, Graham H, Kadler KE, Iozzo RV 1997 Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J Cell Biol 136:729743.
  • 19
    Chakravarti S, Magnuson T, Lass JH, Jepsen KJ, LaMantia C, Carroll H 1998 Lumican regulates collagen fibril assembly: Skin fragility and corneal opacity in the absence of lumican. J Cell Biol 141:12771286.
  • 20
    Xu S, Bianco P, Fisher LW, Longenecker G, Smith E, Goldstein S, Bonadio J, Boskey A, Heegard AM, Sommer B, Satomura K, Dominguez P, Zhao C, Kulkarni AB, Gehron Robey P, Young MF 1998 Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat Genet 20:7882.
  • 21
    Bianco P, Ponzi A, Bonucci E 1984 Basic and “special” stains for plastic sections in bone marrow histopathology, with special reference to May-Grunwald Giemsa and enzyme histochemistry. Basic Appl Histochem 28:265279.
  • 22
    Boyde A, Corsi A, Quarto R, Cancedda R, Bianco P 1999 Osteoconduction in large macroporous hydroxyapatite ceramic implants: Evidence for a complementary integration and disintegration mechanism. Bone 24:579589.
  • 23
    Boyde A, Davy KWM, Jones SJ 1995 Standards for mineral quantitation of human bone by analysis of backscattered electron images. Scanning 17(Suppl V):67.
  • 24
    Howell PGT, Davy KWM, Boyde A 1998 Mean atomic number and backscattered electron coefficient for some materials with low atomic mean number. Scanning 20:3540.
  • 25
    Howell PGT, Boyde A 1998 Monte Carlo simulation of electron backscattering from compounds with low mean atomic number. Scanning 20:4549.
  • 26
    Holbrook KA, Byers PH 1982 Structural abnormalities in the dermal collagen and elastic matrix from the skin of patients with inherited connective tissue disorders. J Invest Dermatol 79:7S16S.
  • 27
    Kobayasi T, Oguchi M, Asboe-Hansen G 1984 Dermal changes in Ehlers-Danlos syndrome. Clin Genet 25:477484.
  • 28
    Steinmann B, Royce PM, Superti-Furga A 1993 The Ehlers-Danlos Syndrome. In: RoycePM, SteinmannB (eds.) Connective Tissue and Its Heritable Disorders. Molecular, Genetic and Medical Aspects. Wiley-Liss, Inc., New York, NY, USA, pp. 351408.
  • 29
    Hausser I, Anton-Lamprecht I 1994 Differential ultrastructural aberrations of collagen fibrils in Ehlers-Danlos syndrome types I-IV as a means of diagnostics and classification. Hum Genet 93:394407.
  • 30
    Mao JR, Bristow J 2001 The Ehlers-Danlos syndrome: On beyond collagens. J Clin Invest 107:10631069.
  • 31
    Hardy MH, Fisher KR, Vrablic OE, Yager JA, Nimmo-Wilkie JS, Parker W, Keeley FW 1988 An inherited connective tissue disease in the horse. Lab Invest 59:253262.
  • 32
    Brown PJ, Young RD, Cripps PJ 1993 Abnormalities of collagen fibrils in a rabbit with a connective tissue defect similar to Ehlers-Danlos syndrome. Res Vet Sci 55:346350.
  • 33
    Birk DE, Fitch JM, Babiarz JP, Doane KJ, Linsenmayer TF 1990 Collagen fibrillogenesis in vitro: Interaction of types I and V collagen regulates fibril diameter. J Cell Sci 95:649657.
  • 34
    Fleischmajer R, Perlish JS, Burgeson RE, Shaikh-Bahai F, Timpl R 1990 Type I and type III collagen interactions during fibrillogenesis. Ann NY Acad Sci 580:161175.
  • 35
    Svensson L, Aszódi A, Reinholt FP, Fässler R, Heinegård D, Oldberg Å 1999 Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon. J Biol Chem 274:96369647.
  • 36
    Ezura Y, Chakravarti S, Oldberg A, Chervoneva I, Birk DE 2000 Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J Cell Biol 151:779788.
  • 37
    Beighton P, De Paepe A, Steinmann B, Tsipouras P, Wenstrup RJ 1998 Ehlers-Danlos syndromes revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK). Am J Med Genet 77:3137.
  • 38
    Ameye L, Aria D, Chen X-D, Gehron Robey P, Chakravarti S, Oldberg A, Young MF 2000 Biglycan and fibromodulin double knockout mice develop ectopic sesamoid bones and premature osteoarthritis in the knee joint. J Bone Miner Res 15:S1;185.
  • 39
    Dolan AL, Arden NK, Grahame R, Spector TD 1998 Assessment of bone in Ehlers Danlos syndrome by ultrasound and densitometry. Ann Rheum Dis 57:630633.
  • 40
    Kresse H, Rosthoj S, Quentin E, Hollmann J, Glossl J, Okada S, Tonnesen T 1987 Glycosaminoglycan-free small proteoglycan core protein is secreted by fibroblasts from a patient with a syndrome resembling progeroid. Am J Hum Genet 41:436453.
  • 41
    Quentin E, Gladen A, Roden L, Kresse H 1990 A genetic defect in the byosinthesis of dermatan sulfate proteoglycan. Galactosyltransferase I deficiency in fibroblasts from a patient with a progeroid syndrome. Proc Natl Acad Sci USA 87:13421346.