Fatal and nonfatal injuries due to suicidal behavior among younger adolescents are of growing concern for many communities. We examined the incidence and patterns of these injuries among persons aged 10–14 years using three databases, two national and a third from Oregon. Suffocation and firearm gunshot were the leading external causes of suicide; poisoning and cutting/piercing were the leading causes of nonfatal self-harm injuries. The most common psychosocial factors associated with those treated in emergency departments for self-harm injuries were psychological conditions; drug/alcohol involvement; and adverse circumstances, including family discord, school problems, and physical/sexual abuse. Analysis of population-based data from these databases are part of the public health approach and can help direct much needed research and prevention efforts that address self-harming behavior in these younger adolescents.