This paper is part of a symposium-in-print dedicated to Professor Eduardo A. Lissi on the occasion of his 70th birthday.
Effect of Solvent Polarity and Viscosity on the Guest Binding Dynamics with Bile Salt Aggregates†
Article first published online: 22 MAY 2007
Photochemistry and Photobiology
Volume 83, Issue 3, pages 494–502, May/June 2007
How to Cite
Yihwa, C. and Bohne, C. (2007), Effect of Solvent Polarity and Viscosity on the Guest Binding Dynamics with Bile Salt Aggregates. Photochemistry and Photobiology, 83: 494–502. doi: 10.1562/2006-09-17-RA-1043
- Issue published online: 22 MAY 2007
- Article first published online: 22 MAY 2007
- Received 17 September 2006; accepted 10 November 2006; published online 20 November 2006
Bile salts form supramolecular aggregates with two binding sites with different properties. The guest binding dynamics to the aggregates and guest protection from species in the aqueous phase were investigated using fluorescence and laser flash photolysis experiments. Sodium cholate, deoxycholate and taurodeoxycholate were used as bile salts and acetonitrile or ethylene glycol were added as co-solvents to water in order to alter the binding properties of 1-ethylnaphthalene and 1-naphthyl-1-ethanol with the aggregates. The binding dynamics are faster and protection efficiencies are lower for guests bound to cholate and in the presence of either co-solvent.