- • Cytomegalovirus is the commonest cause of congenital viral infection in developed countries.
- • Infection is asymptomatic in 90% of individuals.
- • Forty percent of pregnant women with primary infection transmit it to their fetus.
- • Ten percent of infants with congenital cytomegalovirus display clinical manifestations at birth and are at risk of neurological sequelae.
- • While routine antenatal testing is not currently recommended, congenital infection remains a significant obstetric management problem.
- • To learn about the incidence, diagnosis and sequelae of cytomegalovirus in pregnancy.
- • To become familiar with treatment options for the management of congenital cytomegalovirus.
- • Should practitioners recommend routine cytomegalovirus screening in pregnancy?
- • Is a randomised controlled trial necessary before offering treatment with hyperimmune globulin for congenital cytomegalovirus?
Please cite this article as: McCarthy FP, Jones C, Rowlands S, Giles M. Primary and secondary cytomegalovirus in pregnancy. The Obstetrician & Gynaecologist 2009;11:96–100.