Primary and secondary cytomegalovirus in pregnancy
Article first published online: 26 JAN 2011
2009 Royal College of Obstetricians and Gynaecologists
The Obstetrician & Gynaecologist
Volume 11, Issue 2, pages 96–100, April 2009
How to Cite
McCarthy, F. P., Jones, C., Rowlands, S. and Giles, M. (2009), Primary and secondary cytomegalovirus in pregnancy. The Obstetrician & Gynaecologist, 11: 96–100. doi: 10.1576/toag.11.2.096.27482
- Issue published online: 26 JAN 2011
- Article first published online: 26 JAN 2011
- congenital cytomegalovirus;
- polymerase chain reaction;
- • Cytomegalovirus is the commonest cause of congenital viral infection in developed countries.
- • Infection is asymptomatic in 90% of individuals.
- • Forty percent of pregnant women with primary infection transmit it to their fetus.
- • Ten percent of infants with congenital cytomegalovirus display clinical manifestations at birth and are at risk of neurological sequelae.
- • While routine antenatal testing is not currently recommended, congenital infection remains a significant obstetric management problem.
- • To learn about the incidence, diagnosis and sequelae of cytomegalovirus in pregnancy.
- • To become familiar with treatment options for the management of congenital cytomegalovirus.
- • Should practitioners recommend routine cytomegalovirus screening in pregnancy?
- • Is a randomised controlled trial necessary before offering treatment with hyperimmune globulin for congenital cytomegalovirus?
Please cite this article as: McCarthy FP, Jones C, Rowlands S, Giles M. Primary and secondary cytomegalovirus in pregnancy. The Obstetrician & Gynaecologist 2009;11:96–100.