Effect of Pharmacist Intervention and Initiation of Home Blood Pressure Monitoring in Patients with Uncontrolled Hypertension
Article first published online: 17 JAN 2012
2000 Pharmacotherapy Publications Inc.
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Volume 20, Issue 11, pages 1384–1389, November 2000
How to Cite
Mehos, B. M., Saseen, J. J. and MacLaughlin, E. J. (2000), Effect of Pharmacist Intervention and Initiation of Home Blood Pressure Monitoring in Patients with Uncontrolled Hypertension. Pharmacotherapy, 20: 1384–1389. doi: 10.1592/phco.20.17.1384.34891
- Issue published online: 17 JAN 2012
- Article first published online: 17 JAN 2012
This prospective, randomized, controlled study evaluated the impact of pharmacist-initiated home blood pressure monitoring and intervention on blood pressure control, therapy compliance, and quality of life (QOL). Subjects were 36 patients with uncontrolled stage 1 or 2 hypertension. Eighteen subjects received home blood pressure monitors, a diary, and instructions to measure blood pressure twice every morning. Home measurements were evaluated by a clinical pharmacist by telephone, and the patient's family physician was contacted with recommendations if mean monthly values were 140/90 mm Hg or higher. Eighteen control patients did not receive home monitors or pharmacist intervention. Office blood pressure measurements and QOL surveys (SF-36) were obtained at baseline and after 6 months. Mean absolute reductions in systolic and diastolic pressures were significantly reduced from baseline in intervention subjects (17.0 and 10.5 mm Hg, both p<0.0001) but not in controls (7.0 and 3.8 mm Hg, p=0.12 and p=0.09). More intervention subjects (8) had blood pressure values below 140/90 at 6 months compared with controls (4). During the study 83.3% (15) of intervention subjects had drug therapy changes versus 33% (6) of controls (p<0.01). Compliance and QOL were not significantly affected. Our data suggest that the combination of pharmacist intervention with home monitoring can improve blood pressure control in patients with uncontrolled hypertension. This may be related to increased modifications of drug regimens.