Validity of the General Practice Research Database
Article first published online: 16 JAN 2012
2003 Pharmacotherapy Publications Inc.
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Volume 23, Issue 5, pages 686–689, May 2003
How to Cite
Jick, S. S., Kaye, J. A., Vasilakis-Scaramozza, C., Rodríguez, L. A. G., Ruigómez, A., Meier, C. R., Schlienger, R. G., Black, C. and Jick, H. (2003), Validity of the General Practice Research Database. Pharmacotherapy, 23: 686–689. doi: 10.1592/phco.23.5.686.32205
- Issue published online: 16 JAN 2012
- Article first published online: 16 JAN 2012
The United Kingdom General Practice Research Database (GPRD) is an office-based, computer-generated, medical resource designed from its inception to be used for epidemiologic research. A distinct version of the GPRD is maintained by the Boston Collaborative Drug Surveillance Program and has been the source of more than 130 scientific articles primarily addressing drug safety issues. We reviewed evidence related to the validity of the GPRD. Specifically, with our extensive experience with this automated database, we evaluated the quality and completeness of the data that it contains.