Resolution of a Phytobezoar with Aldoph's Meat Tenderizer

Authors

  • Erica L. Baker Pharm.D.,

    1. Departments of Pharmacy Services and Cardiology Hartford Hospital, Hartford, Connecticut
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  • William L. Baker Pharm.D.,

    Corresponding author
    1. Departments of Pharmacy Services and Cardiology Hartford Hospital, Hartford, Connecticut
    2. Department of Pharmacy Practice, University of Connecticut School of Pharmacy, Storrs, Connecticut and the Department of Surgery, Bayhealth Medical Center, Milford, Delaware
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  • David J. Cloney M.D., FACS

    1. Department of Surgery, Bayhealth Medical Center, Milford, Delaware.
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William L. Baker, Pharm.D., BCPS, Department of Cardiology, Hartford Hospital, 80 Seymour Street, CB309, Hartford, CT 06102.

Abstract

A 58-year-old man went to his physician with complaints of midepigastric pain, flatulence, belching, and shortness of breath. During a physical examination, the patient was in no acute distress. The patient underwent an ultrasound examination, which revealed cholelithiasis, a laparoscopic cholecystectomy, which revealed chronic gallbladder disease, and esophagogastroduodenoscopy, which revealed gastritis, a hiatal hernia, and a phytobezoar. To treat the bezoar, the patient was given Adolph's Meat Tenderizer 1 teaspoonful in 8 oz of water before each meal for 7 days. This product contains papain, a proteolytic enzyme, that is thought to cleave protein linkages within bezoars. The patient's symptoms resolved with no adverse events reported, and follow-up endoscopy revealed resolution of the phytobezoar. Although a few other agents are used to treat phytobezoars, little clinical data exist on their safety and effectiveness. Adolph's Meat Tenderizer appears to be a safe and effective treatment for patients with a phytobezoar.

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