• 1
    Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245252.
  • 2
    Kleijmeer MJ, Ossevoort MA, van Veen CJ, et al. MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells. J Immunol 1998; 154: 57155724.
  • 3
    Nijman HW, Kleijmeer MJ, Ossevoort MA, et al. Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells. J Exp Med 1995; 182: 163174.
  • 4
    Randolph GJ, Beaulieu S, Lebecque S, et al. Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science 1998; 282: 480483.
  • 5
    Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 1997; 9: 1016.
  • 6
    Thurnher M, Ramoner R, Gastl G, et al. Bacillus Calmette-Guerin mycobacteria stimulate human blood dendritic cells. Int J Cancer 1997; 70: 128134.
  • 7
    Oh S, McCaffery JM, Eichelberger MC. Dose-dependent changes in influenza virus-infected dendritic cells result in increased allogeneic T-cell proliferation at low, but not high, doses of virus. J Virol 2000; 74: 54605469.
  • 8
    Zhang D, Yang X, Lu H, et al. Immunity to Chlamydia trachomatis mouse pneumonitis induced by vaccination with live organisms correlates with early granulocyte-macrophage colony-stimulating factor and interleukin-12 production and with dendritic cell-like maturation. Infect Immun 1999; 67: 16061613.
  • 9
    Verhasselt V, Buelens C, Willems F et al Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J Immunol 1997; 158: 29192925.
  • 10
    Granucci F, Ferrero E, Foti M, et al. Early events in dendritic cell maturation induced by LPS. Microbes Infect 1999; 1: 10791084.
  • 11
    Cella M, Engering A, Pinet V, et al. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 1997; 388: 782787.
  • 12
    Radvanyi LG, Banerjee A, Weir M, et al. Low levels of interferon-alpha induce CD86 (B7.2) expression and accelerates dendritic cell maturation from human peripheral blood mononuclear cells. Scand J Immunol 1999; 50: 499509.
  • 13
    Kalinski P, Schuitemaker JH, Hilkens, et al. Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation. J Immunol 1998; 161: 28042809.
  • 14
    Chen B, Shi Y, Smith JD, et al. The role of tumor necrosis factor alpha in modulating the quantity of peripheral blood-derived, cytokine-driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting soluble antigens to CD4+ T cells in vitro. Blood 1998; 91: 46524661.
  • 15
    Wong BR, Josien R, Lee SY, et al. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J Exp Med 1997; 186: 20752080.
  • 16
    Jonuleit H, Kuhn U, Muller G, et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol 1997; 27: 31353142.
  • 17
    Tillman BW, de Gruijl TD, Luykx-de Bakker SA, et al. Maturation of dendritic cells accompanies high-efficiency gene transfer by a CD40-targeted adenoviral vector. J Immunol 1999; 162: 63786383.
  • 18
    Caux C, Massacrier C, Vanbervliet B, et al. Activation of human dendritic cells through CD40 cross-linking. J Exp Med 1994; 180: 12631272.
  • 19
    Ranieri E, Herr W, Gambotto A, et al. Dendritic cells transduced with an adenovirus vector encoding Epstein-Barr virus latent membrane protein 2B: a new modality for vaccination. J Virol 1999; 73: 1041610425.
  • 20
    Reis RC, Sorgine MH, Coelho-Sampaio T. A novel methodology for the investigation of intracellular proteolytic processing in intact cells. Eur J Cell Biol 1998; 75: 192197.
  • 21
    Siena S, Di Nicola M, Bregni M, et al. Massive ex vivo generation of functional dendritic cells from mobilized CD34+ blood progenitors for anticancer therapy. Exp Hematol 1995; 23: 14631471.
  • 22
    Calafat J, Nijenhuis M, Janssen H, et al. Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures. J Cell Biol 1994; 126: 967977.
  • 23
    Peters PJ, Raposo G, Neefjes JJ, et al. Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes. J Exp Med 1995; 182: 325334.
  • 24
    Peters PJ, Neefjes JJ, Oorschot V, et al. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature 1991; 349: 669676.
  • 25
    West MA, Lucocq JM, Watts C. Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells. Nature 1994; 369: 147151.
  • 26
    Arkema JM, Schadee-Eestermans IL, Broekhuis-Fluitsma DM, et al. Localization of class II molecules in storage vesicles, endosomes and lysosomes in human dendritic cells. Immunobiology 1991; 183: 396407.
  • 27
    Mommaas AM, Mulder AA, Jordens R, et al. Human epidermal Langerhans cells lack functional mannose receptors and a fully developed endosomal/lysosomal compartment for loading of HLA class II molecules. Eur J Immunol 1999; 29: 571580.
  • 28
    Harding CV, Geuze HJ. Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment. J Immunol 1993; 151: 39883998.
  • 29
    Sanderson F, Kleijmeer MJ, Kelly A, et al. Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science 1994; 266: 15661569.
  • 30
    Pierre P, Denzin LK, Hammond C, et al. HLA-DM is localized to conventional and unconventional MHC class II-containing endocytic compartments. Immunity 1996; 4: 229239.
  • 31
    Turley SJ, Inaba K, Garrett WS, et al. Transport of peptide-MHC class II complexes in developing dendritic cells. Science 2000; 288: 522527.
  • 32
    Inaba K, Turley S, Iyoda T, et al. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J Exp Med 2000; 191: 927936.
  • 33
    Lore K, Sonnerborg A, Spetz AL, et al. Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells. J Immunol Methods 1998; 214: 97111.
  • 34
    Labeur MS, Roters B, Pers B, et al. Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage. J Immunol 1999; 162: 168175.
  • 35
    Corinti S, Fanales-Belasio E, Albanesi C, et al. Cross-linking of membrane CD43 mediates dendritic cell maturation. J Immunol 1999; 162: 63316336.
  • 36
    Sparwasser T, Koch ES, Vabulas RM, et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur J Immunol 1998; 28: 20452054.
  • 37
    Takahashi K, Asagoe K, Zaishun J, et al. Heterogeneity of dendritic cells in human superficial lymph node: in vitro maturation of immature dendritic cells into mature or activated interdigitating reticulum cells. Am J Pathol 1998; 153: 745755.
  • 38
    Metes D, Storkus WJ, Zeevi A, et al. Use of autologous dendritic cells loaded with apoptotic LCL for ex vivo generation of specific CTL from the PBMC of EBV(−) individuals. Transplant Proc 2001; 33:441
  • 39
    Lambert LA, Gibson GR, Maloney M, et al. Equipotent generation of protective antitumor immunity by various methods of dendritic cell loading with whole cell tumor antigens. J Immunother 2001; 24: 232236.
  • 40
    Ferlazzo G, Semino C, Spaggiari GM, et al. Dendritic cells efficiently cross-prime HLA class I-restricted cytolytic T lymphocytes when pulsed with both apoptotic and necrotic cells but not with soluble cell-derived lysates. Int Immunol 2000; 12: 17411747.