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Identification of a Primitive Brain–Derived Neural Stem Cell Population Based on Aldehyde Dehydrogenase Activity
Article first published online: 17 NOV 2005
DOI: 10.1634/stemcells.2005-0217
Copyright © 2006 AlphaMed Press
Additional Information
How to Cite
Corti, S., Locatelli, F., Papadimitriou, D., Donadoni, C., Salani, S., Del Bo, R., Strazzer, S., Bresolin, N. and Comi, G. P. (2006), Identification of a Primitive Brain–Derived Neural Stem Cell Population Based on Aldehyde Dehydrogenase Activity. STEM CELLS, 24: 975–985. doi: 10.1634/stemcells.2005-0217
Publication History
- Issue published online: 2 JAN 2009
- Article first published online: 17 NOV 2005
- Manuscript Accepted: 13 NOV 2005
- Manuscript Received: 14 MAY 2005
References
- 1, . Plasticity of adult stem cells. Cell 2004; 116:639–648.
- 2, , . Stem cell therapy for human neurodegenerative disorders – how to make it work. Nat Med 2004; 10(suppl:S42–S50.
- 3, , et al. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996; 183:1797–1806.
- 4, , et al. ABCG2 – a transporter for all seasons. FEBS Lett 2004; 567:116–120.
- 5, , et al. Membrane properties of rat embryonic multipotent neural stem cells. J Neurochem 2004; 88:212–226.
- 6, , et al. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci U S A 1999; 96:9118–9123.
- 7. The stem-cell niche theory: Lessons from flies. Nat Rev Genet 2002; 3:931–940.
- 8, . Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992; 255:1707–1710.
- 9, , . A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J. Neurosci 1992; 12:4565–4574.
- 10, . A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature 1994; 372:263–266.
- 11, . Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 1996; 175:1–13.
- 12, , et al. In vitro cell density-dependent clonal growth of EGF-responsive murine neural progenitor cells under serum-free conditions. Exp Neurol 1997; 148:147–156.
- 13, , et al. Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 2001; 412:736–739.
- 14, . Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis. J Neurosci 2003; 23:10703–10709.
- 15, . LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 2002; 35:865–875.
- 16, , et al. Direct isolation of human central nervous system cells. Proc Natl Acad Sci U S A 2000; 97:14720–14725.
- 17, , . Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells: In vivo expansion of stem cell phenotype but not functio. Blood 1995;85:1006–1016.
- 18, , et al. Mobilized peripheral blood SS-CloALDHbr cells have the phenotypic and functional properties of primitive haematopoietic cells and their number correlates with engraftment following autologous transplantation. Br J Haematol 2003; 122:99–108.
- 19, , et al. Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity. Stem Cells 2004; 22:1142–1151.
- 20, , et al. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telen-cephalon. Dev Biol 1999; 20:166–188.
- 21, , et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 2000; 28:1–51.
- 22, , et al. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 2001; 19:1129–1133.
- 23, . The mouse brain in stereotaxic coordinates. San Diego: Academic Press. Mouse brain atlas, 1997.
- 24, . Molecular biology of synaptic vesicle-associated proteins. Trends Neurosci 1988; 11:241–242.
- 25, , et al. Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med 2002; 8:268–273.
- 26, . Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. J Neurosci 2002; 22:1784–1793.
- 27, , et al. Large populations of non-clonogenic early apoptotic CD34-positive cells are present in frozen-thawed peripheral blood stem cell transplants. Bone Marrow Transplant 2001; 27:487–498.

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