• 1
    Choudhury C. Role of the microenvironment on hematopoiesis I. Stem cell differentiation into granulocytic and megakaryocytic cell lineage. J Laboratory Clin Med 1989; 114: 378381.
  • 2
    Gordon MY, Clarke D, Atkinson J, et al. Hemopoietic progenitor cell binding to the stromal microenvironment in vitro. Exp Hematol 1990; 18: 837842.
  • 3
    Strobel ES, Gay RE, Greenberg PL. Characterization of the in vitro stromal microenvironment of human bone marrow. Int J Cell Cloning 1986; 4: 341356.
  • 4
    Almici C, Carlo-Stella C, Wagner JE, et al. Umbilical cord blood as a source of hematopoietic stem cells: from research to clinical application. Haematologica 1995; 80: 473479.
  • 5
    Seoh JY, Woo SY, Im SA, et al. Distinct patterns of apoptosis in association with modulation of CD44 induced by thrombopoietin and granulocyte-colony stimulating factor during ex vivo expansion of human cord blood CD34+ cells. Br J Haematol 1999; 107: 176185.
  • 6
    Yoo ES, Ryu KH, Park HY, et al. Myeloid differentiation of human cord blood CD34+ cells during ex vivo expansion using thrombopoietin, flt3-ligand, and/or granulocyte-colony stimulating factor. Br J Haematol 1999; 105: 10341040.
  • 7
    Schmid I, Uittenbogaart CH, Keld B, et al. A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry. J Immunol Methods 1994; 170: 145157.
  • 8
    Philpott NJ, Turner AJ, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood 1996; 87: 22442251.
  • 9
    Hows JM, Bradley BA, Marsh JC, et al. Growth of human umbilical-cord blood in long term haematopoietic cultures. Lancet 1992; 340: 7376.
  • 10
    Nieda M, Nicol A, Denning-Kendall P, et al. Endothelial cell precursors are normal components of human umbilical cord blood. Br J Haematol 1997; 98: 775777.
  • 11
    Ye ZQ, Burkholder K, Qiu P, et al. Establishment of an adherent cell feeder layer from human umbilical cord blood for support of long-term hematopoietic progenitor cell growth. Proc Natl Acad Sci USA 1994; 91: 1214012144.
  • 12
    Traycoff CM, Orazi A, Ladd AC, et al. Proliferation-induced decline of primitive hematopoietic progenitor cell activity is coupled with an increase in apoptosis of ex vivo expanded CD34+ cells. Exp Hematol 1998; 26: 5362.
  • 13
    Sieff CA, Niemeyer CM, Faller DV. The production of hematopoietic growth factors by endothelial accessory cells. Blood Cells 1987; 13: 6574.
  • 14
    Broudy VC, Kaushansky K, Harlan JM, et al. Interleukin 1 stimulates human endothelial cells to produce granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor. J Immunol 1997; 139: 464468.
  • 15
    Lazarus HM, Haynesworth SE, Gerson SL, et al. Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant 1995; 16: 557564.
  • 16
    Liu X, Rapp N, Cheng L. Human mesenchymal stem cells enhance ex vivo expansion of human megakaryocyte, erythroid and myeloid progenitors from purified cord blood CD34+ cells. Proceedings from American Society of Hematology Meeting 1998;725a.
  • 17
    Carlo-Stella C, Tabilio A, Regazzi E, et al. Effect of chemotherapy for acute myelogenous leukemia on hematopoietic and fibroblast marrow progenitors. Bone Marrow Transplant 1997; 20: 465471.
  • 18
    Brandt JE, Galy AH, Luens KM, et al. Bone marrow repopulation by human marrow stem cells after long-term expansion culture on a porcine endothelial cell line. Exp Hematol 1998; 26: 950961.