Get access

Estimating bioconcentration factors, lethal concentrations and critical body residues of metals in the mollusks Perna viridis and Mytilus edulis using ion characteristics

Authors

  • Maurits van Kolck,

    1. Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, 6500 GL Nijmegen, The Netherlands
    Search for more papers by this author
  • Mark A.J. Huijbregts,

    1. Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, 6500 GL Nijmegen, The Netherlands
    Search for more papers by this author
  • Karin Veltman,

    1. Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, 6500 GL Nijmegen, The Netherlands
    Search for more papers by this author
  • A. Jan Hendriks

    Corresponding author
    1. Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, 6500 GL Nijmegen, The Netherlands
    • Department of Environmental Science, Institute for Water and Wetland Research, Radboud University Nijmegen, P.O. Box 9010, 6500 GL Nijmegen, The Netherlands; Published on the Web 11/28/2007
    Search for more papers by this author

Abstract

Quantitative structure–activity relationships (QSARs) for metal bioconcentration factors (BCF) and median acute lethal water concentrations (LC50) were developed for two species of mollusks, Perna viridis and Mytilus edulis. These endpoints were related to four metal ion characteristics, the covalent index (χ2mr) (r represents the ion radius in Å), the softness index (σp), the hydrolysis constant (Koh) and the ionic index (Z2/r). The BCF and LC50 were significantly correlated to χ2mr. The coefficients of determination r2 for the relationships with other metal descriptors were much lower. Critical body residue (CBR) QSARs were derived by multiplying the χ2mr-based BCF and LC50 regressions. The CBRs were independent of the covalent index χ2mr, as BCF and LC50 scaled to χ2mr with slope that had opposite signs. Comparison of the estimated CBRs with independent empirical values confirmed the predicted trends, but substantial deviations were noted too.

Get access to the full text of this article

Ancillary