Following an application from Nutrilinks Sarl, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Belgium, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to hyaluronic acid and protection of the skin against dehydration. The food constituent that is the subject of the health claim, hyaluronic acid, is sufficiently characterised. The claimed effect, protection of the skin against dehydration, is a beneficial physiological effect. The target population proposed by the applicant is the general population. No human studies have been provided from which conclusions could be drawn for the scientific substantiation of the claim. A cause and effect relationship has not been established between the consumption of hyaluronic acid and protection of the skin against dehydration.