In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member State (EMS), Spain, received an application from Sipcam Inagra S.A. to modify the existing maximum residue levels (MRLs) for the active substance mepanipyrim in blackberries, raspberries, peppers and cucumbers. In order to accommodate for the intended uses of mepanipyrim, Spain proposed to raise the existing MRLs to 4 mg/kg on raspberries and blackberries, 1 mg/kg on peppers and 0.5 mg/kg on cucumbers. EFSA assessed only the request for cane fruits and peppers since an MRL proposal of 0.5 mg/kg has already been made for cucumbers in a previous Reasoned Opinion considering the same good agricultural practices (GAP). According to EFSA the data are sufficient to derive MRL proposals of 4 mg/kg on raspberries and blackberries and 1.5 mg/kg on peppers. Adequate analytical enforcement methods are available to control the residues of mepanipyrim on the commodities under consideration. Based on the risk assessment results, EFSA concludes that the proposed uses of mepanipyrim on blackberries, raspberries and peppers will not result in a consumer exposure exceeding the toxicological reference values and therefore are unlikely to pose a consumer health risk.