HLA-Dr-Expressing Langerhans'-Like Cells in Vaginal and Cervical Epithelium

Authors

  • S. Bjercke,

    Corresponding author
    1. Department of Gynecology & Obstetrics, the National Hospital, Rikshospitalet, Oslo, Norway
    2. Department of Pathology, the National Hospital, Rikshospitalet, Oslo, Norway
    3. Department of Dermatology and the Tissue Typing Laboratory, the National Hospital, Rikshospitalet, Oslo, Norway
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  • H. Scott,

    1. Department of Gynecology & Obstetrics, the National Hospital, Rikshospitalet, Oslo, Norway
    2. Department of Pathology, the National Hospital, Rikshospitalet, Oslo, Norway
    3. Department of Dermatology and the Tissue Typing Laboratory, the National Hospital, Rikshospitalet, Oslo, Norway
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  • L. R. Braathen,

    1. Department of Gynecology & Obstetrics, the National Hospital, Rikshospitalet, Oslo, Norway
    2. Department of Pathology, the National Hospital, Rikshospitalet, Oslo, Norway
    3. Department of Dermatology and the Tissue Typing Laboratory, the National Hospital, Rikshospitalet, Oslo, Norway
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  • E. Thorsby

    1. Department of Gynecology & Obstetrics, the National Hospital, Rikshospitalet, Oslo, Norway
    2. Department of Pathology, the National Hospital, Rikshospitalet, Oslo, Norway
    3. Department of Dermatology and the Tissue Typing Laboratory, the National Hospital, Rikshospitalet, Oslo, Norway
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Tissue Typing Laboratory The National Hospital Rikshospitalet, Oslo, 1, Norway

Abstract

Abstract. Sections of ethanol-fixed, paraffin-embedded tissue specimens from human vagina and exocervix were stained by an indirect immunofluorescence method with a rabbit antiserum to HLA-DR antigens. A specific staining of cells having a dendritic appearance were seen. The cells were randomly distributed, mainly in the parabasal cell-layer of the stratified squamous epithelium. The number of dendritic cells was 1-3% of all cells in the cervical epithelium and 1-5% of the cells in the vaginal epithelium. Most probably these cells are Langerhans' cells.

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