Cervical conization and preterm delivery/low birth weight

A systematic review of the literature

Authors


Føde- og Gynzkologisk afd. Y Rigshospitalet Blegdamsvej 9, DK-2100, København Ø, Denmark

Abstract

Objective. Evaluate the effect of cervical conization on preterm birth/low birth weight (LBW).

Design. A systematic review of the literature using external or internal controls.

Results. The typical odds ratio for preterm delivery in women with prior cervical conization using external controls was 3.23 (95% confidence interval 2.29–4.55). Using internal controls the typical odds ratio for LBW was 2.97 (95% confidence interval 1.09 8.05). Using external controls the typical odds ratio for LBW was 2.31 (95% confidence interval 1.33-3.99).

Conclusion. Women with cervical conization are at higher risk for preterm birth than external controls, and the surgical intervention as such is a major determining factor.

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