• 1
    World Health Organization. WHO Report on the Global Tobacco Epidemic, 2011: Warning About the Dangers of Tobacco. Geneva, Switzerland: World Health Organization; 2011.
  • 2
    US Department of Health, Education, and Welfare Public Health Service. Smoking and Health: Report of the Advisory Committee to the Surgeon General of the Public Health Service. Washington, DC: US Department of Health, Education, and Welfare; 1964.
  • 3
    Data and Safety Monitoring Board. Statement Concerning the National Lung Screening Trial. Bethesda, MD: National Cancer Institute; 2010. Accessed October, 28, 2010.
  • 4
    National Lung Screening Trial Research Team, Aberle DR, Adams AM, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011; 365: 395-409.
  • 5
    Howlander N, Noone AM, Krapcho M, et al, eds. SEER Cancer Statistics Review, 1975-2008. Bethesda, MD: National Cancer Institute; 2011.
  • 6
    Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013; 63: 000-000.
  • 7
    Howlander N, Noone AM, Krapcho M, et al, eds. SEER Cancer Statistics Review, 1975-2009. Bethesda, MD: National Cancer Institute; 2012.
  • 8
    National Cancer Institute. Cancer Trends Progress Report-2011/2012 Update. Bethesda, MD: National Cancer Institute; 2012. Accessed October 17, 2012.
  • 9
    Bain C, Feskanich D, Speizer FE, et al. Lung cancer rates in men and women with comparable histories of smoking. J Natl Cancer Inst. 2004; 96: 826-834.
  • 10
    Bach PB, Elkin EB, Pastorino U, et al. Benchmarking lung cancer mortality rates in current and former smokers. Chest. 2004; 126: 1742-1749.
  • 11
    Halpern MT, Gillespie BW, Warner KE. Patterns of absolute risk of lung cancer mortality in former smokers. J Natl Cancer Inst. 1993; 85: 457-464.
  • 12
    Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ. 2004; 328: 1519.
  • 13
    Smith BD, Smith GL, Hurria A, Hortobagyi GN, Buchholz TA. Future of cancer incidence in the United States: burdens upon an aging, changing nation. J Clin Oncol. 2009; 27: 2758-2765.
  • 14
    Fontana RS, Sanderson DR, Woolner LB, et al. Screening for lung cancer. A critique of the Mayo Lung Project. Cancer. 1991; 67( suppl 4): 1155-1164.
  • 15
    Berlin NI. Overview of the NCI Cooperative Early Lung Cancer Detection Program. Cancer. 2000; 89: 2349-2351.
  • 16
    Frost JK, Ball WC Jr, Levin ML, et al. Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study. Am Rev Respir Dis. 1984; 130: 549-554.
  • 17
    Kubik A, Polak J. Lung cancer detection. Results of a randomized prospective study in Czechoslovakia. Cancer. 1986; 57: 2427-2437.
  • 18
    Melamed MR, Flehinger BJ, Zaman MB, Heelan RT, Perchick WA, Martini N. Screening for early lung cancer. Results of the Memorial Sloan-Kettering study in New York. Chest. 1984; 86: 44-53.
  • 19
    Eddy D. ACS report on the cancer-related health checkup. CA Cancer J Clin. 1980; 30: 193-240.
  • 20
    Kramer BS, Gohagan J, Prorok PC, Smart C. A National Cancer Institute sponsored screening trial for prostatic, lung, colorectal, and ovarian cancers. Cancer. 1993; 71: 589-593.
  • 21
    Black WC. Lung cancer. In: Kramer BS, Gohagan JK, Prorok PC, eds. Cancer Screening: Theory and Practice. New York: Marcel Dekker, Inc; 1999: 327-377.
  • 22
    Muhm JR, Miller WE, Fontana RS, Sanderson DR, Uhlenhopp MA. Lung cancer detected during a screening program using four-month chest radiographs. Radiology. 1983; 148: 609-615.
  • 23
    Kaneko M, Eguchi K, Ohmatsu H, et al. Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography. Radiology. 1996; 201: 798-802.
  • 24
    Sone S, Li F, Yang ZG, et al. Results of three-year mass screening programme for lung cancer using mobile low-dose spiral computed tomography scanner. Br J Cancer. 2001; 84: 25-32.
  • 25
    Henschke CI, McCauley DI, Yankelevitz DF, et al. Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet. 1999; 354: 99-105.
  • 26
    Ford LG, Minasian LM, McCaskill-Stevens W, Pisano ED, Sullivan D, Smith RA. Prevention and early detection clinical trials: opportunities for primary care providers and their patients. CA Cancer J Clin. 2003; 53: 82-101.
  • 27
    Gohagan JK, Marcus PM, Fagerstrom RM, et al; LUNG SCREENING STUDY RESEARCH GROUP. Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer. Lung Cancer. 2005; 47: 9-15.
  • 28
    van Iersel CA, de Koning HJ, Draisma G, et al. Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON). Int J Cancer. 2007; 120: 868-874.
  • 29
    Infante M, Lutman FR, Cavuto S, et al; DANTE Study Group. Lung cancer screening with spiral CT: baseline results of the randomized DANTE trial. Lung Cancer. 2008; 59: 355-363.
  • 30
    Lopes Pegna A, Picozzi G, Mascalchi M, et al; ITALUNG Study Research Group. Design, recruitment and baseline results of the ITALUNG trial for lung cancer screening with low-dose CT. Lung Cancer. 2009; 64: 34-40.
  • 31
    Field JK, Baldwin D, Brain K, et al; UKLS Team. CT screening for lung cancer in the UK: position statement by UKLS investigators following the NLST report. Thorax. 2011; 66: 736-737.
  • 32
    Pedersen JH, Ashraf H, Dirksen A, et al. The Danish randomized lung cancer CT screening trial–overall design and results of the prevalence round. J Thorac Oncol. 2009; 4: 608-614.
  • 33
    Bach PB, Mirkin JN, Oliver TK, et al. Benefits and harms of CT screening for lung cancer: a systematic review. JAMA. 2012; 307: 2418-2429.
  • 34
    Field JK, Smith RA, Duffy SW, et al. The Liverpool Statement 2005: priorities for the European Union/United States spiral computed tomography collaborative group. J Thorac Oncol. 2006; 1: 497-498.
  • 35
    Field JK, Smith RA, Aberle DR, et al. International Association for the Study of Lung Cancer Computed Tomography Screening Workshop 2011 report. J Thorac Oncol. 2012; 7: 10-19.
  • 36
    Tabar L, Duffy SW, Yen MF, et al. All-cause mortality among breast cancer patients in a screening trial: support for breast cancer mortality as an end point. J Med Screen. 2002; 9: 159-162.
  • 37
    Infante M, Cavuto S, Lutman FR, et al; DANTE Study Group. A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial. Am J Respir Crit Care Med. 2009; 180: 445-453.
  • 38
    Oken MM, Hocking WG, Kvale PA, et al; PLCO Project Team. Screening by chest radiograph and lung cancer mortality: the Prostate, Lung, Colorectal, and Ovarian (PLCO) randomized trial. JAMA. 2011; 306: 1865-1873.
  • 39
    Cox LS, Clark MM, Jett JR, et al. Change in smoking status after spiral chest computed tomography scan screening. Cancer. 2003; 98: 2495-2501.
  • 40
    Townsend CO, Clark MM, Jett JR, et al. Relation between smoking cessation and receiving results from three annual spiral chest computed tomography scans for lung carcinoma screening. Cancer. 2005; 103: 2154-2162.
  • 41
    MacRedmond R, McVey G, Lee M, et al. Screening for lung cancer using low dose CT scanning: results of 2 year follow up. Thorax. 2006; 61: 54-56.
  • 42
    Styn MA, Land SR, Perkins KA, Wilson DO, Romkes M, Weissfeld JL. Smoking behavior 1 year after computed tomography screening for lung cancer: effect of physician referral for abnormal CT findings. Cancer Epidemiol Biomarkers Prev. 2009; 18: 3484-3489.
  • 43
    American College of Radiology Imaging Network. ACRIN #6654: Contemporary Screening for the Detection of Lung Cancer. Philadelphia, PA: American College of Radiology Imaging Network; 2004: 1-97.
  • 44
    Byrne MM, Weissfeld J, Roberts MS. Anxiety, fear of cancer, and perceived risk of cancer following lung cancer screening. Med Decis Making. 2008; 28: 917-925.
  • 45
    van den Bergh KA, Essink-Bot ML, Borsboom GJ, et al. Short-term health-related quality of life consequences in a lung cancer CT screening trial (NELSON). Br J Cancer. 2010; 102: 27-34.
  • 46
    van den Bergh KA, Essink-Bot ML, Borsboom GJ, Scholten ET, van Klaveren RJ, de Koning HJ. Long-term effects of lung cancer computed tomography screening on health-related quality of life: the NELSON trial. Eur Respir J. 2011; 38: 154-161.
  • 47
    Brenner DJ. Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer. Radiology. 2004; 231: 440-445.
  • 48
    Berrington de Gonzalez A, Kim KP, Berg CD. Low-dose lung computed tomography screening before age 55: estimates of the mortality reduction required to outweigh the radiation-induced cancer risk. J Med Screen. 2008; 15: 153-158.
  • 49
    Lee TY, Chhem RK. Impact of new technologies on dose reduction in CT. Eur J Radiol. 2010; 76: 28-35.
  • 50
    Kubik AK, Parkin DM, Zatloukal P. Czech Study on Lung Cancer Screening: post-trial follow-up of lung cancer deaths up to year 15 since enrollment. Cancer. 2000; 89 ( suppl 11): 2363-2368.
  • 51
    Marcus PM, Bergstralh EJ, Fagerstrom RM, et al. Lung cancer mortality in the Mayo Lung Project: impact of extended follow-up. J Natl Cancer Inst. 2000; 92: 1308-1316.
  • 52
    Reich JM. A critical appraisal of overdiagnosis: estimates of its magnitude and implications for lung cancer screening. Thorax. 2008; 63: 377-383.
  • 53
    American Lung Association. Guidance on Lung Cancer Screening. Washington, DC: American Lung Association; 2012. Accessed September 14, 2012.
  • 54
    Wood DE, Eapen GA, Ettinger DS, et al. Lung cancer screening. J Natl Compr Canc Netw. 2012; 10: 240-265.
  • 55
    Jaklitsch MT, Jacobson FL, Austin JH, et al. The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups. J Thorac Cardiovasc Surg. 2012; 144: 33-38.