The first 3 authors contributed equally to this work.
Recent progress in pancreatic cancer
Article first published online: 15 JUL 2013
Copyright © 2013 American Cancer Society, Inc.
CA: A Cancer Journal for Clinicians
Volume 63, Issue 5, pages 318–348, September/October 2013
How to Cite
Wolfgang, C. L., Herman, J. M., Laheru, D. A., Klein, A. P., Erdek, M. A., Fishman, E. K. and Hruban, R. H. (2013), Recent progress in pancreatic cancer. CA: A Cancer Journal for Clinicians, 63: 318–348. doi: 10.3322/caac.21190
DISCLOSURES: Supported by National Institutes of Health grants P30 CA006973 and P50 CA62924. Dr. Hruban and Dr. Klein receive royalty payments from Myriad Genetics for the PALB2 invention.
- Issue published online: 6 SEP 2013
- Article first published online: 15 JUL 2013
- Manuscript Revised: 22 MAR 2013
- Manuscript Accepted: 22 MAR 2013
- Manuscript Received: 11 FEB 2013
- pancreatic neoplasms;
- molecular biology;
- radiation oncology;
- medical oncology
Pancreatic cancer is currently one of the deadliest of the solid malignancies. However, surgery to resect neoplasms of the pancreas is safer and less invasive than ever, novel drug combinations have been shown to improve survival, advances in radiation therapy have resulted in less toxicity, and enormous strides have been made in the understanding of the fundamental genetics of pancreatic cancer. These advances provide hope but they also increase the complexity of caring for patients. It is clear that multidisciplinary care that provides comprehensive and coordinated evaluation and treatment is the most effective way to manage patients with pancreatic cancer. CA Cancer J Clin 2013;63:318-348. ©2013 American Cancer Society.