Fertility issues in cancer survivorship

Authors

  • Jonathan D. Kort MD,

    1. Resident, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, CA
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  • Michael L. Eisenberg MD,

    1. Assistant Professor, Department of Urology, Stanford University School of Medicine, Palo Alto, CA
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  • Leah S. Millheiser MD,

    1. Clinical Assistant Professor, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, CA
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  • Lynn M. Westphal MD

    Corresponding author
    1. Associate Professor, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, CA
    • Corresponding author: Lynn Westphal, MD, Department of Obstetrics and Gynecology, Stanford University Medical Center, 900 Welch Rd, Suite 20, Palo Alto, CA 94304; lynnw@stanford.edu

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  • DISCLOSURES: Through the work of his deceased father, Jonathan D. Kort, MD, and his family receive royalties from My Egg Bank, LLC and My Egg Bank North America, 2 donor oocyte banks. Dr. Kort has no role in the management of either corporation. Dr. Michael L. Eisenberg, MD, is an advisor to and owns stock in Sandstone Diagnostics. Dr. Leah S. Millheiser has received consulting fees from ExploraMed Inc and Shionogi Inc outside the submitted work.

Abstract

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Breakthroughs in cancer diagnosis and treatment have led to dramatic improvements in survival and the need to focus on survivorship issues. Chemotherapy and radiotherapy can be gonadotoxic, resulting in impaired fertility. Techniques to help cancer survivors reproduce have been improving over the past decade. Discussion of the changes to a patient's reproductive health after cancer treatment is essential to providing comprehensive quality care. The purpose of this review is to aid in pre- and posttreatment counseling, focusing on fertility preservation and other strategies that may mitigate risks to the patient's reproductive, sexual, and overall health. CA Cancer J Clin 2014;64:118–134. © 2013 American Cancer Society.

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