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External beam radiation therapy for prostate cancer†
Article first published online: 31 DEC 2008
Copyright © 2000 American Cancer Society
CA: A Cancer Journal for Clinicians
Volume 50, Issue 6, pages 349–375, November/December 2000
How to Cite
Horwitz, E. M. and Hanks, G. E. (2000), External beam radiation therapy for prostate cancer. CA: A Cancer Journal for Clinicians, 50: 349–375. doi: 10.3322/canjclin.50.6.349
- Issue published online: 31 DEC 2008
- Article first published online: 31 DEC 2008
Men with non-metastatic prostate cancer have many treatment options. For over 35 years, radiation therapy has been a mainstay of treatment for this disease. With improvements in technology and better use of pretreatment prognostic factors, such as prostate specific antigen level and Gleason score, biochemical and clinical results have steadily improved.
This article reviews the current status of radiation therapy in the treatment of prostate cancer. Results of treatment utilizing three-dimensional conformal and conventional techniques are compared and contrasted. The appropriate use of adjuvant hormones and particle beam therapy in the management of this disease is also discussed. Finally, the toxicity and future directions of radiation therapy in the treatment of prostate cancer are addressed.