• 1
    Fainsinger R, Miller MJ, Bruera E, et al. Symptom control during the last week of life. J Palliat Care 1991; 7: 511.
  • 2
    Addington-Hall J, McCarthy M. Dying from cancer: Results of a national population-based investigation. Palliat Med 1995; 9: 295305.
  • 3
    Osoba D, Warr DG, Fitch MI, et al. Guidelines for the optimal management of chemotherapy-induced nausea and vomiting: a consensus. Can J Oncol 1995; 5: 381400.
  • 4
    Bruera E, Seifert L, Watanabe S, et al. Chronic nausea in advanced cancer patients: A retrospective assessment of a metoclopramide-based anti-emetic regimen. J Pain Symptom Manage 1996; 11: 147153.
  • 5
    Kurtz ME, Kurtz JC, Given CC, Given B. Concordance of cancer patient and caregiver symptom reports. Cancer Pract 1996; 4: 185190.
  • 6
    Morrow GR, Roscoe JA, Hynes HE, et al. Progress in reducing anticipatory nausea and vomiting. Support Care Cancer 1998; 6: 4650.
  • 7
    Osoba D, Zee B, Warr D, et al. Effect of post-chemotherapy nausea and vomiting on health-related quality of life. Support Care Cancer 1997; 5: 307313.
  • 8
    Grant M. Nausea and vomiting, quality of life, and the oncology nurse. Oncol Nurs Forum 1997; 24:(7 Suppl): 57.
  • 9
    Pickett M, Cooley ME, Gordon DB. Palliative Care: Past, present and future perspectives. Semin Oncol Nurs 1998; 14: 8694.
  • 10
    Merriam Webster's Collegiate Dictionary, ed 10. Springfield, MA, Merriam-Webster Inc., 1998.
  • 11
    World Health Organization. Cancer pain relief and palliative care: report of a WHO Expert Committee; Technical Report Series 804. Geneva, WHO, 1990.
  • 12
    Hanson EJ, Cullihall K. Palliative nursing care of a man with terminal cancer. Brit J Nursing 1996; 5: 473474, 476–479.
  • 13
    Brant JM. The art of palliative care: living with hope, dying with dignity. Oncol Nurs Forum 1998 25: 9951004.
  • 14
    Rhodes VA, Watson PM, Johnson MH, et al. Patterns of nausea, vomiting and distress in patients receiving antineoplastic drug protocols. Oncol Nurs Forum 1987; 14: 3544.
  • 15
    Morrow GR, Hickok JT, Rosenthal SN. Progress in reducing nausea and emesis. Comparisons of ondansetron (Zogran), granisetron (Kytril), and tropisetron (Navoban). Cancer 1995; 76: 343357.
  • 16
    Rhodes VA, McDaniel RW. Measuring nausea, vomiting, and retching, in Frank-Stromborg M, Olsen SJ (eds): Instruments for Clinical Health-Care Research, ed 2. Boston, Jones & Bartlett, 1997, pp 509518.
  • 17
    Ahmedzai S, Brooks D. Transdermal fentanyl versus sustained-release oral morphine in cancer pain: preference, efficacy, and quality of life. The TTS-Fentanyl Comparative Trial Group. J Pain Symptom Manage 1997; 13: 254261.
  • 18
    Ashby M, Fleming B, Wood M, Somogyi A. Plasma morphine glucuronide (M3G and M6G) concentations in hospice inpatients. J Pain Symptom Manage 1997; 14, 157167.
  • 19
    Burge FI. Dehydration symptoms of palliative care cancer patients. J Pain Symptom Manage 1993; 8: 454464.
  • 20
    Currow DC, Coughlan M., Fardell B, Cooney NJ. Use of ondansetron in palliative medicine. J Pain Symptom Manage, 1997; 13: 302307.
  • 21
    Doyle C, Pintilie M, Crump M, et al. Do outcomes meet expectations in patients undergoing palliative chemotherapy for advanced ovarian cancer? (Meeting abstract). Proc Annu Meet Am Soc Clin Oncol 1997; 16: A1475.
  • 22
    Roila F, Ciccarese G, Palladino MA, De Angelis V. Prevention of radiotherapy-induced emesis. Tumori 1998; 84: 274278.
  • 23
    Blacklow RS (ed). MacBryde's Signs and Symptoms: applied pathologic physiology and clinical interpretation, ed 6. Philadelphia, Lippincott, 1983.
  • 24
    Rhodes VA, Watson PM. Symptom distress - The concept; past and present. Semin Oncol Nurs 1987; 3: 242247.
  • 25
    McDaniel RW, Rhodes VA. Symptom experience: The management of symptom occurrence and symptom distress. Semin Oncol Nurs 1995; 11: 232234.
  • 26
    Johnson MH, Rhodes VA. Patient education, in Perry, M. (ed): Chemotherapy Source Book, ed 3. Baltimore, MD, Lippincott, Williams & Wilkins, In Press.
  • 27
    Rhodes VA, Watson PM, McDaniel RW, et al. Expectation and occurrence of postchemotherapy side effects: nausea and vomiting. Cancer Pract 1995; 3: 247253.
  • 28
    McCorkle R, Young K. Development of a symptom distress scale. Cancer Nurs 1978; 1: 373378.
  • 29
    A model for symptom management. The University of California, San Francisco School of Nursing Symptom Management Faculty Group. Image J Nurs Sch 1994; 26: 2726.
  • 30
    Rhodes VA, Watson PM, Johnson MH. Development of reliable and valid measures of nausea and vomiting. Cancer Nurs 1984; 7: 3341.
  • 31
    Dodd MJ, Onishi K, Dibble SL, Larson PJ. Differences in nausea, vomiting and retching between younger and older outpatients receiving cancer chemotherapy. Cancer Nurs 1996; 19: 155161.
  • 32
    Grunberg SM. Nausea and Vomiting, in Haskell CM (ed): Cancer Treatment, ed 5. Philadelphia, PA, WB Saunders, 2001, pp 327331.
  • 33
    Veyrat-Follet C, Farinotti R, Palmer JL. Physiology of chemotherapy-induced emesis and antiemetic therapy: Predictive models for evaluation of new compounds. Drugs 1997; 53: 206234.
  • 34
    Fozard JR. 5-HT3 receptors and cytotoxic drug-induced vomiting. Trends Pharmacol Sci 1987; 8: 444445.
  • 35
    Kris MG, Radford JE, Pizzo BA, et al. Use of an NK1 receptor antagonist to prevent delayed emesis after cisplatin. J Natl Cancer Inst 1997; 89: 817818.
  • 36
    Herrstedt J. Antiemetic research: a look to the future. Support Care Cancer 1998; 6: 812.
  • 37
    Gralla RJ. Antiemetic Therapy, in Bast RC, Kufe DW, Pollock RE, et al (eds): Cancer Medicine, ed 5. Lewiston, NY, BC Decker Inc., 2000, pp 22432250.
  • 38
    McDaniel RW, Rhodes VA. Development of a preparatory sensory information video tape for women receiving chemotherapy for breast cancer. Cancer Nurs 1998; 21: 143148.
  • 39
    Rhodes VA, McDaniel RW, Hanson B, et al. Sensory perception of patients on selected antineoplastic chemotherapy protocols. Cancer Nurs 1994; 17: 4551.
  • 40
    Leventhal H, Johnson J. Laboratory and field experimentation: development of a theory of self-regulation, in Wooldridge PJ, Schmitt MH, Skipper JK, Leonard RC (eds): Behavioral Science and Nursing Theory, St. Louis, Mosby, 1983, pp 189212.
  • 41
    Johnson JE, Fieler VK, Wlasowicz GS, et al. The effects of nursing care guided by self regulation theory on coping with radiation therapy. Oncol Nurs Forum 1997; 24: 10411050.
  • 42
    Johnson JE, Lauver DR, Nail LM. Process of coping with radiation. J Consult Clin Psychol 1989; 57: 358364.
  • 43
    de Wit R, van den Berg H, Burghouts J, et al. Initial high anti-emetic efficacy of granisetron with dexamethasone is not maintained over repeated cycles. Brit J Cancer 1998; 77: 14871491.
  • 44
    Andrykowski M., Jacobsen PB, Marks E, et al. Prevalence, predictors, and course of anticipatory nausea in women receiving chemotherapy for breast cancer. Cancer 1988; 62: 26072613.
  • 45
    Andrykowski MA. The role of anxiety in the development of anticipatory nausea in cancer chemotherapy: A review and synthesis. Psychosom Med 1990; 52: 458475.
  • 46
    Kvale G, Hugdahl K, Asbjornsen A, et al. Anticipatory nausea and vomiting in cancer patients. J Consult Clin Psychol 1991; 59: 894898.
  • 47
    Fredrikson M, Hurtsti T, Salmi P, et al. Conditioned nausea after cancer chemotherapy and autonomic nervous system conditionability. Scand J Psychol 1993; 34: 318329.
  • 48
    Kvale G, Pschyol C, Hugdahl K. Cardiovascular conditioning and anticipatory nausea and vomiting in cancer patients. Behav Med 1994; 20: 7883.
  • 49
    Christman K, Muss HB, Case LD, Stanley V. Chemotherapy of metastatic breast cancer in the elderly: The Piedmont Oncology Association experience. JAMA 1992; 268: 5762.
  • 50
    Jacobsen PB, Redd WH. The development and management of chemotherapy related anticipatory nausea and vomiting. Cancer Invest 1988; 6: 329336.
  • 51
    Broussard CN, Richter JE. Nausea and vomiting of pregnancy. Gastroenterol Clin North Am 1998; 27: 123151.
  • 52
    Paech MJ, Pavy TJ, Kristensen JH, Wojnar-Horton RE. Postoperative nausea and vomiting: development of a management protocol. Anaesth Intensive Care 1998; 26: 152155.
  • 53
    Fujii Y, Toyooka H, Tanaka H. Prevention of PONV with granisetron, droperidol and metoclopramide in female patients with history of motion sickness. Can J Anaesth 1997; 44: 820824.
  • 54
    D'Acquisto R, Tyson LB, Gralla RJ, et al. The influence of a chronic high alcohol intake on chemotherapy-induced nausea and vomiting 1986; Proceedings of ASCO:257.
  • 55
    Spiess JL, Adelstein DJ, Hines JD. Evaluation of ethanol as an antiemetic in patients receiving cisplatin. Clin Ther 1987; 9: 400404.
  • 56
    Olver IN, Craft PS, Clingan PR, et al. An open multicentre study of tropisetron for cisplatin-induced nausea and vomiting. Med J Aust 1996; 164: 337340.
  • 57
    Desbiens NA, Mueller-Rizner N, Connors AF, Wenger NS. The relationship of nausea and dyspnea to pain in seriously ill patients. Pain 1997; 71: 149156.
  • 58
    Mercadante S, Casuccio A., Fulfaro F. The course of symptom frequency and intensity in advanced cancer patients followed at home. J Pain Symptom Manage 2000; 20: 104112.
  • 59
    Mannix KA. Palliation of nausea and vomiting, in Doyle D, Hanks GWC, MacDonald N (eds): Oxford Textbook of Palliative Medicine, ed 2. New York, Oxford University Press, 1998, pp 489499.
  • 60
    Hursti TJ, Avall-Lundquits E, Baorjerson S, et al. Impact of tumour burden on chemotherapy induced nausea and vomiting. Br J Cancer 1996; 74: 11141119.
  • 61
    Bruera ED, MacEachern TJ, Spachynski KA, et al. Comparison of the efficacy, safety and pharmacokinetics of controlled release and immediate release metoclopramide for the management of chronic nausea in patients with advanced cancer. Cancer 1994; 74: 32043211.
  • 62
    Del Favero A, Tonato M, Roila F. Issues in the measurement of nausea. Br J Cancer Suppl 1992; 19: S69S71.
  • 63
    Rhodes VA, McDaniel RW. The Index of nausea, vomiting, and retching: a new format of the Index of Nausea, Vomiting. Oncol Nurs Forum 1999; 26: 889894.
  • 64
    Cotanch PH. Relaxation training for control of nausea and vomiting in patients receiving chemotherapy. Cancer Nurs 1983; 6: 277283.
  • 65
    Rhodes VA, McDaniel RW, Matthews CA. Hospice patient and nurses' perceptions of self-care deficits based on symptom experience. Cancer Nurs 1998; 21: 312319.
  • 66
    Rhodes VA, McDaniel RW, Homan SS, et al. An instrument to measure symptom experience. Symptom occurrence and symptom distress. Cancer Nurs 2000; 23: 4954.
  • 67
    Portenoy RK, Thaler HT, Kornblith AB, et al. The Memorial Symptom Assessment Scale: An instrument for the evaluation of symptom prevalence, characteristics and distress. Europ J Cancer 1994; 30A: 13261336.
  • 68
    Brunton LL. Agents affecting gastrointestinal water flux and motility; emesis and antiemetics; bile acids and pancreatic enzymes, in Hardman JG, Limbird LE, Molinoff PB, et al (eds): Goodman & Gilman's The Pharmacological Basis of Therapeutics, ed 9. New York, McGraw-Hill, Health Professions Division, 1996, pp 928993.
  • 69
    Gandara DR, Harvey WH, Monaghan GG, et al. The delayed-emesis syndrome from cisplatin: phase III evaluation of ondansetron versus placebo. Semin Oncol 1992; 19: 6771.
  • 70
    Wickham R. Nausea and vomiting, in Yarbro CH, Frogge MH, Goodman M (eds): Cancer Symptom Management, ed 2. Boston, Jones and Bartlett, 1999, pp 228259.
  • 71
    Maule WH. Gastrointestinal toxicity of chemotherapeutic agents, in M Perry (ed) Chemotherapy Source Book, ed 2. Baltimore, MD, Williams & Wilkins, 1996, pp 697707.
  • 72
    Simms SG, Rhodes VA, Madsen, RW. Comparison of prochlorperazine and lorazepam antiemetic regimens in the control of postchemotherapy symptoms. Nurs Res 1993; 42: 234239.
  • 73
    Kris MG, Baltzer L, Pisters KM, Tyson LB. Enhancing the effectiveness of the specific serotonin antagonists. Combination antiemetic therapy with dexamethasone. Cancer 1993; 72: 34363442.
  • 74
    Mystakidou K, Befon S, Liossi C, Vlachos L. Comparison of tropisetron and chlorpromazine combinations in the control of nausea and vomiting of patients with advanced cancer. J Pain Symptom Manage 1998; 15: 176184.
  • 75
    McCabe M, Smith FP, MacDonald JS, et al. Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy. Invest New Drugs 1988; 6: 243246.
  • 76
    Schwartz RH, Beveridge RA. Marijuana as an antiemetic drug: how useful is it today? Opinions from clinical oncologists. J Addict Dis 1994; 13: 5365.
  • 77
    Tortorice PV, O'Connell MB. Management of chemotherapy-induced nausea and vomiting. Pharmacotherapy 1990; 10(2): 129145.
  • 78
    Clark PA. The ethics of medical marijuana: government restrictions vs. medical necessity. J Public Health Policy 2000; 21: 4060.
  • 79
    Gonzalez-Rosales F, Walsh D. Intractable nausea and vomiting due to gastrointestinal mucosal metastases relived by tetrahydrocannabinol (dronabinol). J Pain Symptom Manage 1997; 14: 311314.
  • 80
    Gralla RJ, Osoba D, Kris MG, Kirkbride P, et al. Recommendations for the Use of Antiemetics: Evidence-Based, Clinical Practice Guidelines (Adopted on February 18, 1999) accessed from, American Society of Clinical Oncology.
  • 81
    American Society of Health-System Pharmacists. ASHP therapeutic guidelines on the pharmacologic management of nausea and vomiting in adult and pediatric patients receiving chemotherapy or radiation therapy or undergoing surgery. Am J Health Syst Pharm 1999; 56:729764. (
  • 82
    Wickham RS, Rehwaldt M, Kefer C, et al. Taste changes experienced by patients receiving chemotherapy Oncol Nurs Forum 1999; 26: 697706.
  • 83
    Strang P. Quality of life is the most important goal of nutritional support of the dying Lakartidningen 2000; 97: 11411144.
  • 84
    Anonymous. NIH Consensus Conference. Acupuncture. JAMA 1998; 280: 15181524.
  • 85
    Fan CF, Tanhui E, Joshi S, et al. Acupressure treatment for prevention of postoperative nausea and vomiting. Anesth Analg 1997; 84: 821825.
  • 86
    Stein DJ, Birnbach DJ, Danzer BI, et al. Acupressure versus intravenous metoclopramide to prevent nausea and vomiting during spinal anesthesia for cesarean section. Anesth Analg 1997; 84: 342345.
  • 87
    Aikins Murphy P. Alternative therapies for nausea and vomiting of pregnancy. Obstet Gynecol 1998; 91: 149155.
  • 88
    Dundee JW, Yang J. Prolongation of the antiemetic action of p6 acupuncture by acupressure in patients having cancer chemotherapy. J R Soc Med 1990; 83(6): 360362.
  • 89
    Dundee JW, Ghaly RG, Fizpatrick KT, et al. Acupuncture prophylaxis of cancer chemotherapy-induced sickness. J R Soc Med 1989; 82: 268271.
  • 90
    Dibble SL, Chapman J, Mack KA, Shih AS. Acupressure for nausea: results of a pilot study. Oncol Nurs Forum 2000: 27: 4147.
  • 91
    Brown S, North D, Marvel MK, Fons R. Acupressure wrist bands to relieve nausea and vomiting in hospice patients: do they work?. Am J Hosp Palliat Care 1992; 9: 2629.
  • 92
    Frank JM. The effects of music therapy and guided visual imagery on chemotherapy induced nausea and vomiting. Oncol Nurs Forum 1985; 12: 4752.
  • 93
    Ezzone S, Baker C, Rosselet R, Terepka E. Music as an adjunct to antiemetic therapy. Oncol Nurs Forum 1998; 25: 15511556.
  • 94
    Bayuk L. Relaxation Techniques: an adjunct therapy for cancer patients. Semin Oncol Nurs 1985; 1: 147150.
  • 95
    Cotanch PH, Strom S. Progressive muscle relaxation as antiemetic therapy for cancer patients. Oncol Nurs Forum 1987; 14: 3337.
  • 96
    Morrow GR, Hickok JT. Behavioral treatment of chemotherapy-induced nausea and vomiting. Oncology 1993; 7(12): 839; discussion 93–94, 97.
  • 97
    Yoo HJ. Efficacy of relaxation training (RT) and guided imagery (GI) in reducing the side effects of cancer chemotherapy. Proc Annu Meet Am Soc Clin Oncol 1997; 16: A302.
  • 98
    Arakawa S. Relaxation to reduce nausea, vomiting and anxiety induced by chemotherapy in Japanese patients. Cancer Nurs 1997; 20: 342349.
  • 99
    Scott DW, Donahue DC, Mastrovito RC, Hakes TB. Comparative trial of clinical relaxation and an antiemetic drug regimen in reducing chemotherapy-related nausea and vomiting. Cancer Nurs 1986; 9: 178187.
  • 100
    Troesch LM, Rodehaver CB, Delaney EA, Yanes B. The influence of guided imagery on chemotherapy-related nausea and vomiting. Oncol Nurs Forum 1993; 20: 11791185.
  • 101
    Vigano A, Watanabe S, Bruera E. Anorexia and cachexia in advanced cancer patients. Cancer Surv 1994; 21: 99115.