Emerging Technologies in Screening for Colorectal Cancer: CT Colonography, Immunochemical Fecal Occult Blood Tests, and Stool Screening Using Molecular Markers

Authors

  • Dr. Bernard Levin MD,

    1. Levin is Vice President for Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX
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  • Dr. Durado Brooks MD, MPH,

    1. Brooks is Director, Colorectal and Prostate Cancers, Cancer Control Sciences Department, American Cancer Society, Atlanta, GA
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  • Dr. Robert A. Smith PhD,

    1. Smith is Director, Cancer Screening, Cancer Control Sciences Department, American Cancer Society, Atlanta, GA
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  • Ms. Amy Stone MCo

    1. Stone is President, Amy Stone Scientific and Medical Communications, Inc., Decatur, GA
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    • Author disclosures: Bernard Levin, MD, serves on the Scientific Advisory Board of Enterix, Inc. Theodore Levin, MD, has received research support from EXACT Sciences Corporation, and anticipates commencing a study with and receiving research support from Enterix, Inc. Richard Wender, MD, serves on the Scientific Advisory Board of Enterix, Inc.


Abstract

The American Cancer Society's (ACS) Colorectal Cancer Advisory Group held a workshop on new technologies for the early detection of colorectal cancer and adenomatous polyps as part of a regular review of ACS guidelines for colorectal cancer screening. The Advisory Group formally reviewed CT colonography, immunochemical fecal occult blood tests (FOBT), and stool screening using molecular markers, and also addressed other technologies including capsule video endoscopy. With the exception of immunochemical stool testing, the ACS has determined that at this time there is insufficient evidence to recommend these technologies for routine colorectal cancer screening. Based on recommendations of the Advisory Group, only a minor modification has been made to the ACS's Recommendations for Screening and Surveillance of the Early Detection of Adenomatous Polyps and Colorectal Cancer.

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