American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography

Authors

  • Dr. Debbie Saslow PhD,

    1. Saslow is Director, Breast and Gynecologic Cancer, Cancer Control Science Department, American Cancer Society, Atlanta, GA
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  • Dr. Carla Boetes MD, PhD,

    1. Boetes is Professor, Department of Radiology, University Medical Center Nijmegen, Nijmegen, The Netherlands
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  • Dr. Wylie Burke MD, PhD,

    1. Burke is Chair; and Professor of Medical History and Ethics, University of Washington, Seattle, WA
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  • Dr. Steven Harms MD,

    1. Harms is Radiologist, The Breast Center of Northwest Arkansas, Fayetteville, AR; and Clinical Professor of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR
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  • Dr. Martin O. Leach PhD,

    1. Leach is Professor of Physics as Applied to Medicine; Co-Chairman, Section of Magnetic Resonance; and Co-Director, Cancer Research; UK Clinical Magnetic Resonance Research Group, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Surrey, UK
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  • Dr. Constance D. Lehman MD, PhD,

    1. Lehman is Professor of Radiology; and Section Head of Breast Imaging, University of Washington Medical Center and the Seattle Cancer Care Alliance, Seattle, WA
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  • Dr. Elizabeth Morris MD,

    1. Morris is Director, Breast MRI, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY
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  • Dr. Etta Pisano MD,

    1. Pisano is Vice Dean for Academic Affairs; Kenan Professor of Radiology and Biomedical Engineering; and Director, UNC Biomedical Research Imaging Center, UNC School of Medicine, University of North Carolina, Chapel Hill, NC
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  • Dr. Mitchell Schnall MD, PhD,

    1. Schnall is Matthew J. Wilson Professor of Radiology; and Associate Chair for Research, Department of Radiology, University of Pennsylvania, Philadelphia, PA
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  • Dr. Stephen Sener MD,

    1. Sener is Vice Chairman, Department of Surgery, Evanston Northwestern Health Care, Evanston, IL; and Professor of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
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  • Dr. Robert A. Smith PhD,

    1. Smith is Director, Cancer Screening, Cancer Control Science Department, American Cancer Society, Atlanta, GA
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  • Dr. Ellen Warner MD,

    1. Warner is Associate Professor, Department of Medicine, University of Toronto and Toronto-Sunnybrook Regional Cancer Centre, Toronto, Canada
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  • Dr. Martin Yaffe PhD,

    1. Yaffe is Senior Scientist, Imaging Research, Sunnybrook Health Sciences Centre; and Professor, Departments of Medical Imaging and Medical Biophysics, University of Toronto, Toronto, Canada
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  • Ms. Kimberly S. Andrews,

    1. Andrews is Research Associate, Cancer Control Science Department, American Cancer Society, Atlanta, GA
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  • Dr. Christy A. Russell MD,

    1. Russell is Associate Professor of Medicine, Keck School of Medicine, University of Southern California; and Co-Director of USC/Norris Breast Center, Los Angeles, CA.
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  • for the American Cancer Society Breast Cancer Advisory Group


Abstract

New evidence on breast Magnetic Resonance Imaging (MRI) screening has become available since the American Cancer Society (ACS) last issued guidelines for the early detection of breast cancer in 2003. A guideline panel has reviewed this evidence and developed new recommendations for women at different defined levels of risk. Screening MRI is recommended for women with an approximately 20–25% or greater lifetime risk of breast cancer, including women with a strong family history of breast or ovarian cancer and women who were treated for Hodgkin disease. There are several risk subgroups for which the available data are insufficient to recommend for or against screening, including women with a personal history of breast cancer, carcinoma in situ, atypical hyperplasia, and extremely dense breasts on mammography. Diagnostic uses of MRI were not considered to be within the scope of this review.

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