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Arndt Guentsch, Susanne Busch, Karin Seidler, Ulrike Kraft, Sandor Nietzsche, Philip M. Preshaw, Julia N. Chromik, Eike Glockmann, Klaus D. Jandt and Bernd W. Sigusch Biomimetic Mineralization: Effects on Human Enamel In Vivo Advanced Engineering Materials 12

Article first published online: 7 OCT 2010 | DOI: 10.1002/adem.201080008

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Dental caries, and tooth surface loss by erosion, abrasion, and attrition lead to irreversible loss of dental tissue. Enamel is a highly mineralized acellular tissue and cannot be regenerated after tooth eruption. Currently available restorative materials, such as composites, replace lost tooth structure and improve function and aesthetics. However, these materials have no structural similarities to natural tooth structure. The efficacy of an experimental biomimetic mineralization-kit was tested in a clinical pilot study in patients with hypersensitive teeth. Enamel defects were effectively treated by addition of a fluoroapatite layer.

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