Humphrey H. P. Yiu, Hong-jun Niu, Ellen Biermans, Gustaaf van Tendeloo and Matthew J. Rosseinsky Designed Multifunctional Nanocomposites for Biomedical Applications Advanced Functional Materials 20
The assembly of multifunctional nanocomposite materials is demonstrated by exploiting the molecular sieving property of SBA-16 nanoporous silica. Cages of SBA-16 are used to host iron oxide magnetic nanoparticles, leaving a pore volume of 0.29 cm3 g−1 accessible for drug storage. The outer surface of the particles is decorated by antibodies using (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) coupling. The resulting material offers a dual magnetic and antibody-targeting drug delivery mechanism.
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