E-mail

E-mail a Wiley Online Library Link

Deok-Ho Kim, Chang-Ho Seo, Karam Han, Keon Woo Kwon, Andre Levchenko and Kahp-Yang Suh Cell Migration: Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy (Adv. Funct. Mater. 10/2009) Advanced Functional Materials 19

Version of Record online: 18 MAY 2009 | DOI: 10.1002/adfm.200990041

Thumbnail image of graphical abstract

A novel microtextured cell substrate with variable local density and anisotropy as a platform for guided cell migration is presented by A. Levchenko, K.-Y. Suh, et al. on page 1579. A simple, scalable, and cost-effective technique, capillary force lithography, is used to fabricate precise microtopographic features on an optically transparent glass coverslip. Live cell motility is found to be extremely sensitive to variation in the local density and anisotropy of rectangular lattices, with cell elongation and speed decreasing on a symmetric lattice. Cells integrate orthogonal contact guidance cues when determining the direction of their orientation and movement.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH