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Daniel Macaya, Karen K. Ng and Myron Spector Injectable Collagen–Genipin Gel for the Treatment of Spinal Cord Injury: In Vitro Studies Advanced Functional Materials 21

Article first published online: 18 OCT 2011 | DOI: 10.1002/adfm.201101720

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The addition of genipin (0.25–1 mM) to soluble type I collagen imparts substantial dose dependent increases in shear modulus immediately after gelation, as compared to collagen alone. This range of genipin concentrations is chosen because it is compatible with mesenchymal and neural stem cell encapsulation and survival within the gel.

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