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Yi Jia, Yue Cui, Jinbo Fei, Mingchun Du, Luru Dai, Junbai Li and Yang Yang Construction and Evaluation of Hemoglobin-Based Capsules as Blood Substitutes Advanced Functional Materials 22

Version of Record online: 31 JAN 2012 | DOI: 10.1002/adfm.201102737

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Biocompatible, biodegradable, and blood-compatible hemoglobin-based microcapsules used as blood substitutes are successfully fabricated by covalent layer-by-layer assembly. Given the advantages of the layer-by-layer assembly technique, the construction and behavior of these hemoglobin-based capsules are controllable and adjustable, which makes the obtained capsules promising candidates for applications as blood substitutes, oxygen carriers, and in other biomedical fields.

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