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Nikola Kojic, Eleanor M. Pritchard, Hu Tao, Mark A. Brenckle, Jessica P. Mondia, Bruce Panilaitis, Fiorenzo Omenetto and David L. Kaplan Focal Infection Treatment using Laser-Mediated Heating of Injectable Silk Hydrogels with Gold Nanoparticles Advanced Functional Materials 22

Article first published online: 25 MAY 2012 | DOI: 10.1002/adfm.201200382

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A single 10-minute laser treatment of a subcutaneous infection in mice preserves the general tissue architecture, while achieving a bactericidal effect, and even results in complete eradication in some cases. The unique materials platform presented can provide the basis for an alternative treatment of focal infections.

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