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Seung-Hyun Jun, Kwanghee Kim, Hyo Jin An, Byoung Chan Kim, Chung Hee Sonn, Miju Kim, Junsang Doh, Cassian Yee, Kyung-Mi Lee and Jungbae Kim Ethanol-Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4+ T Lymphocytes Advanced Functional Materials 22

Article first published online: 25 JUN 2012 | DOI: 10.1002/adfm.201200657

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Electrospun and alcohol-dispersed PS-PSMA nanofibers, allowing for facile conjugation of antibodies, could be used as an innovative cell isolation/enrichment and support/release platform. This work opens up a new potential for an innovative immune cell therapy, in which specific immune cells are isolated by antibody-conjugated nanofibers and directly delivered to the target disease sites under the controlled and sustained release of immune cells via in vivo activation.

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