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Sujin Cho, On Hwang, Iljea Lee, Gayoung Lee, Donghyuck Yoo, Gilson Khang, Peter M. Kang and Dongwon Lee Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated-Inflammatory Diseases Advanced Functional Materials 22

Version of Record online: 12 JUN 2012 | DOI: 10.1002/adfm.201200773

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Hydrogen peroxide is generated in large amounts during inflammatory responses and therefore has great potential as a diagnostic and therapeutic marker. Chemiluminescent and antioxidant micelles are developed as novel theranostic agents for hydrogen peroxide-associated inflammatory diseases. The micelles are capable of imaging hydrogen peroxide that is endogenously generated in the lipopolysaccharide (LPS)-stimulated ankle of mice. They also exert potent antioxidant and anti-apoptotic activity.

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