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Connie Wu, Seyma Aslan, Adeline Gand, Joseph S. Wolenski, Emmanuel Pauthe and Paul R. Van Tassel Porous Nanofilm Biomaterials Via Templated Layer-by-Layer Assembly Advanced Functional Materials 23

Article first published online: 10 AUG 2012 | DOI: 10.1002/adfm.201201042

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Hydrogel-like biomaterials are often too soft to support robust cell adhesion, yet methods to increase mechanical rigidity can compromise their bioactivity. Nanoparticle templating is reported as a strategy toward porous, layer-by-layer assembled, thin polyelectrolyte films with sufficient mechanical rigidity to promote robust cell adhesion and high loading capacity for bioactive species. This is potentially ideal for cell-contacting applications.

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