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Ana C. Mendes, Katherine H. Smith, Esther Tejeda-Montes, Elisabeth Engel, Rui L. Reis, Helena S. Azevedo and Alvaro Mata Co-Assembled and Microfabricated Bioactive Membranes Advanced Functional Materials 23

Version of Record online: 3 SEP 2012 | DOI: 10.1002/adfm.201201065

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Hierarchically structured self-assembled membranes that incorporate both biomolecular and topographical signaling elements are fabricated in a single step process. The spontaneous co-assembly of hyaluronic acid and a multidomain peptide of opposite charge guided by microfabricated structures provides a simple method for producing a complex membrane scaffold for tissue engineering applications.

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