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Yung Chang, Yu-Ju Shih, Chia-Jung Lai, Hsiao-Han Kung and Shaoyi Jiang Blood-Inert Surfaces via Ion-Pair Anchoring of Zwitterionic Copolymer Brushes in Human Whole Blood Advanced Functional Materials 23

Article first published online: 28 SEP 2012 | DOI: 10.1002/adfm.201201386

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Blood-inert surfaces are achieved in human whole blood by a simple and robust method using ion-pair anchoring of diblock copolymers with well-defined zwitterionic and charged segments. A systematic investigation is performed to study how chain lengths and surface packing densities of zwitterionic polymer brushes affect blood compatibility. This provides a new class of materials to effectively control biofouling in complex media for charged biomaterials.

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