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Eleanor M. Pritchard, Thomas Valentin, Bruce Panilaitis, Fiorenzo Omenetto and David L. Kaplan Antibiotic-Releasing Silk Biomaterials for Infection Prevention and Treatment Advanced Functional Materials 23

Version of Record online: 26 SEP 2012 | DOI: 10.1002/adfm.201201636

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Silk biomaterials represent a novel, customizable platform for focal antibiotic delivery with advantageous properties including biocompatibility, tunable biodegradation rate, stabilizing effects, water-based processing, and diverse material formats. Injectable and implantable antibiotic-releasing silk biomaterials (including hydrogels, microspheres, films, nanofilm coatings, and antibiotic-loaded fibers) repress local bacteria growth in vitro and in vivo.

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