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Anirudha Singh, Jianan Zhan, Zhaoyang Ye and Jennifer H. Elisseeff Modular Multifunctional Poly(ethylene glycol) Hydrogels for Stem Cell Differentiation Advanced Functional Materials 23

Article first published online: 13 SEP 2012 | DOI: 10.1002/adfm.201201902

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Poly(ethylene glycol) is used to create synthetic hydrogel microenvironments for cells, but the ether backbone lacks sites for functionalization. Here, supramolecular chemistry is applied to create modular hydrogels using α-cyclodextrins modified with biological and chemical functional groups with independently controlled crosslinking densities designed to direct stem cell functions.

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