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Michael A. Daniele, Stella H. North, Jawad Naciri, Peter B. Howell, Stephen H. Foulger, Frances S. Ligler and André A. Adams Rapid and Continuous Hydrodynamically Controlled Fabrication of Biohybrid Microfibers Advanced Functional Materials 23

Version of Record online: 11 SEP 2012 | DOI: 10.1002/adfm.201202258

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The combination of hydrogel chemistry and fiber morphology provides an ideal platform for the encapsulation of cells for many large-scale applications. A microfluidic device is used to continuously produce hydrogel fibers of various sizes encapsulating viable bacteria. Within the fiber shaping microchannel, cells are localized in the hydrodynamically constrained pre-gel, and upon exposure to light, a continuous biohybrid fiber forms.

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