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Na Li, Zhengze Yu, Wei Pan, Yaoyao Han, Tingting Zhang and Bo Tang A Near-Infrared Light-Triggered Nanocarrier with Reversible DNA Valves for Intracellular Controlled Release Advanced Functional Materials 23

Article first published online: 2 DEC 2012 | DOI: 10.1002/adfm.201202564

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A novel near-infrared light-triggered nanocarrier is developed based on mesoporous silica-coated gold nanorods with reversible DNA valves. The release amount of the cargo molecules can be controlled precisely by adjusting the irradiation time and the laser on-off cycles. The controlled release can be accomplished in living cells. Moreover, the therapeutic effect toward cancer cells can also be regulated.

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