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Yongzhong Wang, Leming Sun, Sijia Yi, Yujian Huang, Scott C. Lenaghan and Mingjun Zhang Naturally Occurring Nanoparticles from Arthrobotrys oligospora as a Potential Immunostimulatory and Antitumor Agent Advanced Functional Materials 23

Article first published online: 4 DEC 2012 | DOI: 10.1002/adfm.201202619

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A nematode-trapping fungus, Arthrobotrys oligospora, cultured in a sitting drop culture system, produces abundant spherical nanoparticles. The fungal nanoparticles have an average size of 360–370 nm, with a zeta potential of –33 mV. They contain glycosaminoglycan and protein components, and demonstrate potential activity as an immunostimulatory and antitumor agent for cancer immunochemotherapy.

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