Xiaojiao Kang, Ziyong Cheng, Dongmei Yang, Ping'an Ma, Mengmeng Shang, Chong Peng, Yunlu Dai and Jun Lin Drug Delivery: Design and Synthesis of Multifunctional Drug Carriers Based on Luminescent Rattle-Type Mesoporous Silica Microspheres with a Thermosensitive Hydrogel as a Controlled Switch (Adv. Funct. Mater. 7/2012) Advanced Functional Materials 22
Multifunctional rattle-type microspheres integrating the advantages of being mesoporous, luminescent, and temperature responsive into one single entity are fabricated. As reported by Ziyong Cheng, Jun Lin, and co-workers on page 1470, the composite shows red emission and can potentially be applied as a spin-lattice relaxation time (T1)-positive contrast agent due to the Gd2O3:Eu3+ core. The rate of drug release can be regulated via a change in temperature due to controlled switching of the hydrogel.
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