Biana Godin, Ciro Chiappini, Srimeenakshi Srinivasan, Jenolyn F. Alexander, Kenji Yokoi, Mauro Ferrari, Paolo Decuzzi and Xuewu Liu Drug Delivery: Discoidal Porous Silicon Particles: Fabrication and Biodistribution in Breast Cancer Bearing Mice (Adv. Funct. Mater. 20/2012) Advanced Functional Materials 22
Porous silicon (pSi) disks, rendered from a scanning electron microscopy (SEM) image, are shown on the background of an immuno-histochemistry fluorescent microscopy image from a breast tumor. On page 4225, Biana Godin, Xuewu Liu, and co-workers describe the microfabrication of discoidal pSi nanoparticles with precisely controlled morphologies made by direct photolithographic patterning and demonstrate the geometry-dependent, preferable accumulation of the pSi disks over spherical nanoparticles in orthotopic murine models of breast cancer.
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