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Xuejiao Song, Hua Gong, Shengnan Yin, Liang Cheng, Chao Wang, Zhiwei Li, Yonggang Li, Xiaoyong Wang, Gang Liu and Zhuang Liu Ultra-Small Iron Oxide Doped Polypyrrole Nanoparticles for In Vivo Multimodal Imaging Guided Photothermal Therapy Advanced Functional Materials 24

Version of Record online: 23 SEP 2013 | DOI: 10.1002/adfm.201302463

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A novel type of multifunctional theranostic nanoparticles is developed by encapsulating ultra-small iron oxide nanoparticles (IONPs) with polypyrrole (PPy), on top of which polyethylene glycol (PEG) is coated. The obtained IONP@PPy-PEG nanoparticles with strong superparamagnetism and high near-infrared absorbance enable in vivo dual-modal magnetic resonance and photoacoustic imaging-guided photothermal therapy, achieving excellent cancer ablation effect in animal experiments.

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