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Judith K. Hohmann and Georg von Freymann Influence of Direct Laser Written 3D Topographies on Proliferation and Differentiation of Osteoblast-Like Cells: Towards Improved Implant Surfaces Advanced Functional Materials 24

Version of Record online: 25 AUG 2014 | DOI: 10.1002/adfm.201401390

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Proliferation and differentiation can be influenced via three-dimensional designer topographies. This systematic study shows how osteoblast-like cells grow on different well-defined structures, fabricated by direct laser writing. Proliferation is significantly increased (170%) on particular structures compared to unstructured surfaces (100%) with identical chemical composition. The results might lead to novel implants with decreased implant failure rates.

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