Frances Harding, Renee Goreham, Robert Short, Krasimir Vasilev and Nicolas H. Voelcker Surface Bound Amine Functional Group Density Influences Embryonic Stem Cell Maintenance Advanced Healthcare Materials 2
A surface chemistry gradient reveals the sensitivity of embryonic stem cell behavior to amine functional group density on the underlying substrate. On a single surface, a range of octadiene/allylamine plasma co-polymer ratios are screened for support of cell attachment and stem cell marker expression. Optimal surface chemistry conditions are able to partly override differentiation induced by cytoskeletal disruption.
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