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Frances Harding, Renee Goreham, Robert Short, Krasimir Vasilev and Nicolas H. Voelcker Surface Bound Amine Functional Group Density Influences Embryonic Stem Cell Maintenance Advanced Healthcare Materials 2

Version of Record online: 2 NOV 2012 | DOI: 10.1002/adhm.201200119

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A surface chemistry gradient reveals the sensitivity of embryonic stem cell behavior to amine functional group density on the underlying substrate. On a single surface, a range of octadiene/allylamine plasma co-polymer ratios are screened for support of cell attachment and stem cell marker expression. Optimal surface chemistry conditions are able to partly override differentiation induced by cytoskeletal disruption.

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