E-mail a Wiley Online Library Link

Wuxiao Ding, Naohiro Kameta, Hiroyuki Minamikawa, Momoyo Wada, Toshimi Shimizu and Mitsutoshi Masuda Hybrid Organic Nanotubes with Dual Functionalities Localized on Cylindrical Nanochannels Control the Release of Doxorubicin Advanced Healthcare Materials 1

Article first published online: 30 AUG 2012 | DOI: 10.1002/adhm.201200133

Thumbnail image of graphical abstract

The construction, via a co-assembly approach, of hybrid organic nanotubes with dual functionalities (–COOH and benzyloxycarbonyl) localized on cylindrical nanochannels is demonstrated. The nanotubes effectively encapsulate doxorubicin (Dox) into their nanospace via complex formation between –COO groups and the –NH3+ of Dox, and sustained release of doxorubicin is achieved owing to hydrophobic interaction between benzyloxycarbonyl groups and the anthracycline moiety of doxorubicin.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.