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Yun-Long Wu, Hui Yin, Feng Zhao and Jun Li Multifunctional Hybrid Nanocarriers Consisting of Supramolecular Polymers and Quantum Dots for Simultaneous Dual Therapeutics Delivery and Cellular Imaging Advanced Healthcare Materials 2

Version of Record online: 26 OCT 2012 | DOI: 10.1002/adhm.201200183

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A novel multifunctional hybrid nanocarrier consisting of a red fluorescence quantum dot core and a star-shaped cationic β-cyclodextrin polymer shell is demonstrated. Chemotherapeutic drug paclitaxel is supramolecularly preloaded into the nanocarrier, which co-delivers the drug and DNA with an enhanced gene expression, while the quantum dot core allows simultaneous cellular imaging using laser scanning confocal microscopy.

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