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Wei Qu, Shan Ren, Ying Kuang, Xue-Jun Jiang, Ren-Xi Zhuo and Xian-Zheng Zhang Mimicking the Biological Ligand–Receptor Principle for Universal Target Gene Delivery Mediated by Avidin–Biotin Interaction Advanced Healthcare Materials 2

Version of Record online: 8 OCT 2012 | DOI: 10.1002/adhm.201200206

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A facile and flexible targeting gene-delivery strategy is reported by mimicking the biological ligand–receptor principle based on avidin–biotin interaction. In vitro and in vivo investigations demonstrate that this strategy provides a simple, but universal alternative for potential target gene delivery as well as drug delivery.

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