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Hanene Ali-Boucetta, Dimitrios Bitounis, Rahul Raveendran-Nair, Ania Servant, Jeroen Van den Bossche and Kostas Kostarelos Purified Graphene Oxide Dispersions Lack In Vitro Cytotoxicity and In Vivo Pathogenicity Advanced Healthcare Materials 2

Article first published online: 4 OCT 2012 | DOI: 10.1002/adhm.201200248

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The preparation of high-purity graphene oxide (GO), with high aqueous dispersibility, that can be reliably used in biological investigations is described. Characterization of pure GO compared with conventional GO prepared by the Hummers method is offered. Purified GO shows lack of cytotoxic responses in vitro and no inflammatory responses or granuloma formation after intraperitoneal injection of living animals (in vivo).

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