Phat L. Tran, Jessica R. Gamboa, Katherine E. McCracken, Mark R. Riley, Marvin J. Slepian and Jeong-Yeol Yoon Nanowell-Trapped Charged Ligand-Bearing Nanoparticle Surfaces: A Novel Method of Enhancing Flow-Resistant Cell Adhesion Advanced Healthcare Materials 2
A novel method utilizing nanofabrication techniques is used to create surfaces with enhanced endothelial adhesion and retention under flow. The system utilizes nanotexture, charge, and ligands all combined together, uniquely assembled on the substrata surface, to create ensemble nanotextured surfaces. This system may be of particular utility for enhancing flow-resistant endothelialization of cardiovascular devices.
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